109060-64-2

Basic information

• Product Name: 5-(3-methylphenyl)-1,3,4-oxadiazol-2-amine(SALTDATA: FREE)
• Synonyms: 5-(3-methylphenyl)-1,3,4-oxadiazol-2-amine(SALTDATA: FREE);5-(m-tolyl)-1,3,4-oxadiazol-2-amine
• CAS NO: 109060-64-2
• Molecular Formula: C₉H₉N₃O
• Molecular Weight: 175.19
• Mol File: 109060-64-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 74-75 °C
• Boiling Point: 353.2°C at 760 mmHg
• Flash Point: 167.4°C
• Appearance: /
• Density: 1.229g/cm³
• Vapor Pressure: 3.64E-05mmHg at 25°C
• Refractive Index: 1.594
• PKA: -1.11±0.26(Predicted)
• CAS DataBase Reference: 5-(3-methylphenyl)-1,3,4-oxadiazol-2-amine(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-methylphenyl)-1,3,4-oxadiazol-2-amine(SALTDATA: FREE)(109060-64-2)
• EPA Substance Registry System: 5-(3-methylphenyl)-1,3,4-oxadiazol-2-amine(SALTDATA: FREE)(109060-64-2)

Safety Data

• Hazardous Substances Data: 109060-64-2(Hazardous Substances Data)

Usage

General Description

5-(3-methylphenyl)-1,3,4-oxadiazol-2-amine, also known as SALTDATA: FREE, is a chemical compound with the molecular formula C9H8N4O. It is an oxadiazole derivative with a substitution of a 3-methylphenyl group at the fifth position. 5-(3-methylphenyl)-1,3,4-oxadiazol-2-amine(SALTDATA: FREE) has potential applications in pharmaceutical research and drug development due to its unique chemical structure and properties. It may also have uses in analytical chemistry and organic synthesis. Further research and testing are necessary to fully understand the potential uses and effects of this compound.

InChI:InChI=1/C9H9N3O/c1-6-3-2-4-7(5-6)8-11-12-9(10)13-8/h2-5H,1H3,(H2,10,12)

Upstream product

• 16678-30-1 3-methyl-benzaldehyde-semicarbazone 
• 1711-06-4 3-Methylbenzoyl chloride 
• 881-73-2 2-(3-methylbenzoyl)hydrazinecarbothioamide 
• 506-68-3 bromocyane 
• 13050-47-0 3-methylbenzoyl hydrazine 
• 563-41-7 semicarbazide hydrochloride 
• 620-23-5 m-tolyl aldehyde 

Downstream Products

• 36481-48-8 N'-{Imino-[N'-(3-methyl-benzoyl)-hydrazino]-methyl}-hydrazinecarbodithioic acid methyl ester 
• 36371-80-9 N'-{Imino-[N'-(3-methyl-benzoyl)-hydrazino]-methyl}-hydrazinecarbodithioic acid benzyl ester 
• 37423-11-3 N,N-dimethyl-N'-(5-m-tolyl-[1,3,4]oxadiazol-2-yl)-formamidine 

Relevant articles and documents

Synthesis of N-pyrimidin[1,3,4]oxadiazoles and N-pyrimidin[1,3,4]-thiadiazoles from 1,3,4-oxadiazol-2-amines and 1,3,4-thiadiazol-2-amines via Pd-catalyzed heteroarylamination

An efficient and practical procedure was developed to prepare various N-pyrimidin[1,3,4]oxadiazole and thiadiazole scaffolds using a Buchwald-type coupling. The products of this reaction are otherwise difficult to access and could be used as building bloc

Discovery and biophysical characterization of 2-amino-oxadiazoles as novel antagonists of PqsR, an important regulator of Pseudomonas aeruginosa virulence

The human pathogen Pseudomonas aeruginosa employs alkyl quinolones for cell-to-cell communication. The Pseudomonas quinolone signal (PQS) regulates various virulence factors via interaction with the transcriptional regulator PqsR. Therefore, we consider t