109113-97-5

Basic information

• Product Name: IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-TRIFLUOROMETHYL-
• Synonyms: IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-TRIFLUOROMETHYL-;6-CHLORO-2-(TRIFLUOROMETHYL)-IMIDAZO[1,2-B]PYRIDAZINE
• CAS NO: 109113-97-5
• Molecular Formula: C7H3ClF3N3
• Molecular Weight: 221.57
• Product Categories: Halides;Fused Ring Systems
• Mol File: 109113-97-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.68g/cm³
• Refractive Index: 1.59
• Storage Temp.: 2-8°C
• PKA: -0.53±0.30(Predicted)
• CAS DataBase Reference: IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-TRIFLUOROMETHYL-(CAS DataBase Reference)
• NIST Chemistry Reference: IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-TRIFLUOROMETHYL-(109113-97-5)
• EPA Substance Registry System: IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-TRIFLUOROMETHYL-(109113-97-5)

Safety Data

• Hazardous Substances Data: 109113-97-5(Hazardous Substances Data)

Usage

General Description

IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-TRIFLUOROMETHYL- is a chemical compound with the molecular formula C7H2ClF3N4. It is a chlorinated and trifluoromethylated derivative of imidazopyridazine, and it is used in pharmaceutical research as a potential medication for various therapeutic applications. It has been studied for its potential as an anti-cancer agent, as well as for its antiviral and antibacterial properties. IMIDAZO[1,2-B]PYRIDAZINE, 6-CHLORO-2-TRIFLUOROMETHYL- exhibits interesting biological activities and has the potential to be developed into new drugs for the treatment of various diseases.

InChI:InChI=1/C7H3ClF3N3/c8-5-1-2-6-12-4(7(9,10)11)3-14(6)13-5/h1-3H

Upstream product

• 5469-69-2 6-chloro-pyridazin-3-ylamine 
• 431-35-6 3-bromo-1,1,1-trifluoroacetone 
• 431-37-8 3-chloro-1,1,1-trifluoroacetone 

Downstream Products

• 109114-00-3 2-trifluoromethylimidazo<1,2-b>pyridazine 

Relevant articles and documents

Spiro Compounds As NPY Y5 Receptor Antagonists

The present invention relates to novel compounds of formula (I), or a pharmaceutically acceptable salt thereof, wherein R is an aryl or heteroaryl, which may be substituted by one or more: halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, cyano;Z1 is H, C1-C4 alkyl or F;Z is CH2, CH(C1-C4 alkyl), C(C1-C4 alkyl)2 or a bond;A is a 6-10 membered aryl or heteroaryl, which may be substituted by one or more: halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, cyano; or —C(═O)—X; or —O(CH2)0-1R1;B is hydrogen or is a 5-6 membered heteroaryl, or a 4-6 membered heterocycle, or phenyl, which may be substituted by one or more: halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, hydroxyl, cyano; A and B being linked via any atom;R1 is —(C1-C4)alkyl(C1-C4)alkoxy; or C3-C8 cycloalkyl; or R1 is an aryl or heteroaryl, which may be substituted by one or more: halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, cyano; or R1 is a 4-6 membered heterocycle, which may be substituted by one or more: halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, cyano;X is OR2 or NR3R4;R2 is C1-C4 alkyl;R3 is hydrogen or together with R4 and the nitrogen form a 5-6 saturated membered ring;R4 is C3-C8 cycloalkyl; processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as NPY Y5 receptor antagonists and as agents for the treatment and/or prophylaxis of eating disorders such as a binge eating disorder.

Research on heterocyclic compounds. XX. Synthesis of trifluoromethyl derivatives of fused imidazole systems

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