109180-95-2Relevant articles and documents
ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR
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, (2021/06/26)
The invention provides compounds that degrade the epidermal growth factor receptor (EGFR) including mutant forms via the ubiquitination of the EGFR protein and subsequent proteasomal degradation. The compounds are useful for the treatment of various cancers.
HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME
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Paragraph 00219-00221, (2019/04/16)
The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to the CXCR4 pathway.
Enantiospecific first total synthesis of 7a(S)-p-hydroxyphenopyrrozin
Kothapalli, Yugandhar,Puthukanoori, Ravi Kumar,Alapati, Srinivasa Rao
, p. 1891 - 1893 (2012/05/07)
An enantiospecific first total synthesis of metabolite 7a(S)-p- hydroxyphenopyrrozin 2, isolated from the cultured fungi Chromocleista sp. has been achieved starting from readily and abundantly available l-proline. The strategy of synthesis utilizes base