1091820-63-1

Basic information

• Product Name: ethyl 4-(4-chlorophenyl)-1,2-dihydro-6-methyl-2-oxopyrimidine-5-carboxylate
• Synonyms: ethyl 4-(4-chlorophenyl)-1,2-dihydro-6-methyl-2-oxopyrimidine-5-carboxylate
• CAS NO: 1091820-63-1
• Molecular Weight: 292.722
• Mol File: 1091820-63-1.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: ethyl 4-(4-chlorophenyl)-1,2-dihydro-6-methyl-2-oxopyrimidine-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(4-chlorophenyl)-1,2-dihydro-6-methyl-2-oxopyrimidine-5-carboxylate(1091820-63-1)
• EPA Substance Registry System: ethyl 4-(4-chlorophenyl)-1,2-dihydro-6-methyl-2-oxopyrimidine-5-carboxylate(1091820-63-1)

Safety Data

• Hazardous Substances Data: 1091820-63-1(Hazardous Substances Data)

Upstream product

• 5948-71-0 4-(4-chlorophenyl)-5-(ethoxycarbonyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one 
• 141-97-9 ethyl acetoacetate 
• 104-88-1 4-chlorobenzaldehyde 
• 57-13-6 urea 

Downstream Products

• 1245716-50-0 ethyl 4-(4-chlorophenyl)-6-methyl-2-(tosyloxy)pyrimidine-5-carboxylate 
• 1245716-62-4 ethyl 4-(4-chlorophenyl)-6-methyl-2-(piperidin-1-yl)pyrimidine-5-carboxylate 
• 1245716-57-7 ethyl 4-(4-chlorophenyl)-6-methyl-2-morpholinopyrimidine-5-carboxylate 
• 1307273-39-7 ethyl 2-(4-methoxybenzoyloxy)-4-(4-chlorophenyl)-6-methylpyrimidine-5-carboxylate 
• 1307273-37-5 ethyl 2-(benzoyloxy)-4-(4-chlorophenyl)-6-methylpyrimidine-5-carboxylate 
• 1307273-41-1 ethyl 2-(4-chlorobenzoyloxy)-4-(4-chlorophenyl)-6-methylpyrimidine-5-carboxylate 
• 1307273-34-2 ethyl 4-(4-chlorophenyl)-6-methyl-2-phenoxypyrimidine-5-carboxylate 
• 1307273-40-0 ethyl 2-(4-nitrobenzoyloxy)-4-(4-chlorophenyl)-6-methylpyrimidine-5-carboxylate 
• 1448992-17-3 C₁₄H₁₂Cl₂N₂O₂ 
• 1448992-23-1 ethyl 4-(4-chlorophenyl)-2-(4-((7-chloroquinolin-4-yl)amino)butylamino)-6-methylpyrimidine-5-carboxylate 
• 1245716-68-0 ethyl 4-(4-chlorophenyl)-6-methyl-2-(p-tolylthio)pyrimidine-5-carboxylate 

Relevant articles and documents

Microwave-induced one-pot synthesis of pyrimidine-2(1H)-one derivatives as anti-inflammatory agents

A series of pyrimidine-2(1H)-one derivative were obtained by multi-component one-pot synthesis under microwave irradiation. Equimolar quantities of ethylacetoacetate, substituted benzaldehydes and urea undergo condensation followed by cyclizaton in presence of aqueous solution of sodium hydroxide to produce corresponding pyrimidine derivatives. With the help of microwave heating, there is clean reaction with shorter reaction time, environmental-friendly, improved yield as compared to conventional heating method. The structures of the newly synthesized compounds have been established on the basis of their IR, NMR spectral data. These compounds were screened for their anti-inflammatory activity. Some of them were found to possess significant activity as compared to standard drug.

Palladium-catalyzed dehydrogenation of dihydro-heterocycles using isoprene as the hydrogen acceptor without oxidants

An efficient and general method for Pd-catalyzed dehydrogenative aromatization of dihydro-heteroatom compounds without external O2 and H2 is first described. The protocol firstly uses isoprene as a hydrogen acceptor. Various dihydro-

Novel and chemoselective dehydrogenation of 3,4-dihydropyrimidin-2(1h)-ones with 1,4-bis(triphenylphosphonium)-2-butene peroxodisulfate

3,4-Dihydropyrimidin-2(1H)-ones were efficiently converted into the corresponding pyrimidin-2(1H)-ones in high yields within a short period of time on treatment with aqueous acetonitrile using 1,4-bis(triphenylphosphonium)-2- butene peroxodisulfate. Chemo