109216-61-7Relevant articles and documents
Efficient syntheses of exo-granisetron hydrochloride and other potential impurities present in granisetron hydrochloride, an anti-emetic drug
Vishnu, Eda V.R.,Joseph, Suju,Srinivasana, Abayee K.,Gania, Ramesh S.,Reddy, Govindabur R.,Rao, Patakokila V.,Dahanukara, Vilas H.,Ramanatham, Josyula,Devanna, Nayakanti
experimental part, p. 722 - 727 (2012/05/04)
European Pharmacopeia mentions about nine potential impurities in Granisetron hydrochloride. These impurities need to be controlled in the API as described in the Pharmacopeia. Elegant syntheses of four potential impurities in Granisetron hydrochloride are disclosed.
Convenient method for the 3-functionalization of isoindazoles
Bunnell, Aaron,O'Yang, Counde,Petrica, Andra,Soth, Michael J.
, p. 285 - 293 (2007/10/03)
The C-3 position of isoindazoles is readily functionalized by metalation with lithium diisopropylamide followed by reaction with a variety of electrophiles. Copyright Taylor & Francis LLC.
Indazoles as indole bioisosteres: Synthesis and evaluation of the tropanyl ester and amide of indazole-3-carboxylate as antagonists at the serotonin 5HT3 receptor
Fludzinski,Evrard,Bloomquist,Lacefield,Pfeifer,Jones,Deeter,Cohen
, p. 1535 - 1537 (2007/10/02)
-