1092364-02-7

Basic information

• Product Name: 1-((3S)-3-(4-(3-chloro-2,4-difluorophenylamino)-7-methoxyquinazolin-6-yloxy)pyrrolidin-1-yl)pro-2-pen-1-one
• Synonyms: 1-((3S)-3-(4-(3-chloro-2,4-difluorophenylamino)-7-methoxyquinazolin-6-yloxy)pyrrolidin-1-yl)pro-2-pen-1-one
• CAS NO: 1092364-02-7
• Molecular Weight: 460.868
• Mol File: 1092364-02-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-((3S)-3-(4-(3-chloro-2,4-difluorophenylamino)-7-methoxyquinazolin-6-yloxy)pyrrolidin-1-yl)pro-2-pen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-((3S)-3-(4-(3-chloro-2,4-difluorophenylamino)-7-methoxyquinazolin-6-yloxy)pyrrolidin-1-yl)pro-2-pen-1-one(1092364-02-7)
• EPA Substance Registry System: 1-((3S)-3-(4-(3-chloro-2,4-difluorophenylamino)-7-methoxyquinazolin-6-yloxy)pyrrolidin-1-yl)pro-2-pen-1-one(1092364-02-7)

Safety Data

• Hazardous Substances Data: 1092364-02-7(Hazardous Substances Data)

Upstream product

• 179688-52-9 6-hydroxy-7-methoxyquinazolin-4(3H)-one 
• 13794-72-4 3H-6,7-dimethoxyquinazolin-4-one 
• 179688-53-0 6-acetoxy-7-methoxy-3,4-dihydroquinazolin-4-one 
• 5653-40-7 2-Amino-4,5-dimethoxybenzoic acid 
• 612501-62-9 C₁₈H₂₂ClN₃O₄ 
• 574745-97-4 4-chloro-6-hydroxy-7-methoxyquinazoline 
• 179688-54-1 4-chloro-7-methoxyquinazolin-6-yl acetate hydrochloride salt 
• 1092365-53-1 N-(3-chloro-2,4-difluorophenyl)-7-methoxy-6-((3S)-pyrrolidin-3-yloxy)quinazolin-4-amine 
• 814-68-6 acryloyl chloride 

Relevant articles and documents

NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS

The present invention provides a novel amide derivative and a pharmaceutically acceptable salt thereof which selectively and effectively inhibits the growth of cancer cells induced by the overexpression of an epidermal growth factor receptor and also prevents the development of drug resistance caused by the mutation of EGFR tyrosine kinase, and a pharmaceutical composition comprising same as an active ingredient.