109276-71-3

Basic information

• Product Name: (S)-2-tert-Butoxycarbonylamino-pentanedioic acid 1-benzyl ester 5-(2-thioxo-2H-pyridin-1-yl) ester
• Synonyms: (S)-2-tert-Butoxycarbonylamino-pentanedioic acid 1-benzyl ester 5-(2-thioxo-2H-pyridin-1-yl) ester
• CAS NO: 109276-71-3
• Molecular Weight: 446.524
• Mol File: 109276-71-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (S)-2-tert-Butoxycarbonylamino-pentanedioic acid 1-benzyl ester 5-(2-thioxo-2H-pyridin-1-yl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-tert-Butoxycarbonylamino-pentanedioic acid 1-benzyl ester 5-(2-thioxo-2H-pyridin-1-yl) ester(109276-71-3)
• EPA Substance Registry System: (S)-2-tert-Butoxycarbonylamino-pentanedioic acid 1-benzyl ester 5-(2-thioxo-2H-pyridin-1-yl) ester(109276-71-3)

Safety Data

• Hazardous Substances Data: 109276-71-3(Hazardous Substances Data)

Upstream product

• 1121-30-8 1-hydroxy-2(1H)-pyridinethione 
• 30924-93-7 Boc-Glu-OBn 
• 3811-73-2 2-mercaptopyridine-1-oxide sodium salt 
• 24608-52-4 tert-butyl chloroformate 
• 30924-93-7 α-benzyl N^α-(tert-butyloxycarbonyl)-L-glutamate 

Downstream Products

• 115573-14-3 (E)-(S)-6-tert-Butoxycarbonylamino-hept-2-enedioic acid 7-benzyl ester 1-methyl ester 
• 115573-33-6 2-L-N-Boc aminopimelic acid 
• 26630-55-7 (2S)-L-α-Aminopimelic acid 
• 125982-82-3 benzyl N-tert-butoxycarbonyl-2-amino-6-diethoxyphosphonate-L-caproic ester 
• 168264-14-0 (S)-N-tert-butoxycarbonyl-γ-(N4-benzoxycarbonyl-1-cytosinyl)homoalanine 
• 165266-70-6 (S)-4-(6-Amino-purin-9-yl)-2-tert-butoxycarbonylamino-butyric acid benzyl ester 
• 165266-71-7 (S)-2-tert-Butoxycarbonylamino-4-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-butyric acid benzyl ester 
• 186809-38-1 (S)-N-tert-butoxycarbonyl-γ-(N4-benzoxycarbonyl-1-cytosinyl)homoalanine benzyl ester 
• 186809-40-5 4-(2-amino-6-chloro-purin-9-yl)-2-tert-butoxycarbonylamino-butyric acid benzyl ester 
• 864628-89-7 (S)-γ-(9-guaninyl)homoalanine benzyl ester 
• 95656-97-6 benzyl 4-bromo-2-<(tert-butyloxy)carbonylamino>butanoate 
• 119768-47-7 (S)-Boc-Glu(2-chloroethyl)-OBzl 
• 119768-48-8 (S)-2-((tert-butoxycarbonyl)amino)-4-iodobutyric acid benzyl ester 
• 95656-92-1 benzyl (S)-2-((tert-butoxycarbonyl)amino)butanoate 

Relevant articles and documents

Synthesis of N-Boc-α-Amino Acids with Nucleobase Residues as Building Blocks for the Preparation of Chiral PNA (Peptidic Nucleic Acids).

N-Boc-Glutamic acid α-benzyl ester was transformed into 4-bromo-2-(tert-butoxycarbonylamino)-butyric acid benzyl ester using the Barton-Crich protocol.This bromo derivative undergoes nucleophilic substitution with nucleobases to give optically active N-Bo

Side chain homologation of alanyl peptide nucleic acids: Pairing selectivity and stacking

Alanyl peptide nucleic acids (alanyl-PNAs) are oligomers based on a regular peptide backbone with alternating configuration of the amino acids. All side chains are modified by covalently linked nucleobases. Alanyl-PNAs form very rigid, well defined, and l

MANIPULATION OF THE CARBOXYL GROUPS OF α-AMINO-ACIDS AND PEPTIDES USING RADICAL CHEMISTRY BASED ON ESTERS OF N-HYDROXY-2-THIOPYRIDONE

Photolysis of α-amino-acid or peptide esters derived from N-hydroxy-2-thiopyridone in the presence of t-butylthiol affords the expected decarboxylation products in good yield.The reaction can be applied to the α-carboxyl or to the side chain carboxyl of g