109299-79-8

Basic information

• Product Name: 2,4-DI(TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE
• Synonyms: 2,4-Di(tert-butoxy)pyrimidin-5-ylboronic acid hydrate, May contain varying amounts of anhydride, 97%;[2,4-bis(tert-butoxy)pyriMidin-5-yl]boronic acid;2,4-Di(tert-butoxy)pyriMidin-5-ylboronic acid hydrate, 97%, Variable anhydride content
• CAS NO: 109299-79-8
• Molecular Formula: C₁₂H₂₁BN₂O₄
• Molecular Weight: 268.12
• EINECS: 220-753-0
• Mol File: 109299-79-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 431.408 °C at 760 mmHg
• Flash Point: 214.708 °C
• Appearance: /
• Density: 1.134 g/cm³
• Vapor Pressure: 3.29E-08mmHg at 25°C
• Refractive Index: 1.498
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,4-DI(TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DI(TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE(109299-79-8)
• EPA Substance Registry System: 2,4-DI(TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE(109299-79-8)

Safety Data

• Hazardous Substances Data: 109299-79-8(Hazardous Substances Data)

Usage

Uses

2,4-Di(tert-butoxy)pyrimidine-5-boronic Acid is a useful reagent for the synthesis of flexible nucleosides, which could create potential anticancer and antiviral drugs.

InChI:InChI=1/C12H21BN2O4/c1-11(2,3)18-9-8(13(16)17)7-14-10(15-9)19-12(4,5)6/h7,16-17H,1-6H3

Upstream product

• 19752-61-5 5-bromo-2,4-di(tert-butoxy)pyrimidine 

Downstream Products

• 132400-59-0 2,4-di-tert-butoxy-5-(3-methyl-thiophen-2-yl)-pyrimidine 
• 127235-84-1 2,4-di-tert-butoxy-5-(pyridin-2-yl)pyrimidine 
• 127236-15-1 2,4-Di-tert-butoxy-5-pyridin-3-yl-pyrimidine 
• 127236-16-2 2,4-Di-tert-butoxy-5-pyridin-4-yl-pyrimidine 
• 132400-61-4 5-trans-propenyl-2,4-di-t-butoxypyrimidine 
• 178411-13-7 2,4-di-t-butoxy-5-(3'-iodophenyl)pyrimidine 
• 178411-11-5 2,4-di-t-butoxy-5-(3'-aminophenyl)pyrimidine 
• 7306-78-7 2,4-di-tert-butoxy-pyrimidine 
• 1245898-50-3 5-(3-bromo-5-tert-butyl-4-methoxyphenyl)-2,4-di-tert-butoxypyrimidine 
• 1245898-39-8 N-(6-(3-tert-butyl-5-(2,4-di-tert-butoxypyrimidin-5-yl)-4-methoxyphenyl)naphthalen-2-yl)methanesulfonamide 
• 1245899-21-1 2,4-di-tert-butoxy-5-(3-tert-butyl-5-iodo-4-methoxyphenyl)pyrimidine 
• 132400-58-9 2,4-Di-tert-butoxy-5-(3-hexyl-thiophen-2-yl)-pyrimidine 

Relevant articles and documents

Synthesis of 5-fluorovinyl derivatives of pyrimidines via Suzuki-Miyaura coupling and their 1,3-dipolar cycloaddition reactions with nitrones

A simple two-step synthesis of a new class of fluorinated isoxazolidinyl derivatives of pyrimidine is described. The reactions proceed via the Suzuki-Miyaura coupling followed by highly regioselective 1,3-dipolar cycloaddition with nitrones. Removal of th