109308-81-8

Basic information

• Product Name: 2-(2,4-Dichlor-5-nitrobenzoyl)-3-(isopropylidenhydrazino)acrylsaeure-ethylester
• CAS NO: 109308-81-8
• Molecular Weight: 388.207
• Mol File: 109308-81-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2,4-Dichlor-5-nitrobenzoyl)-3-(isopropylidenhydrazino)acrylsaeure-ethylester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,4-Dichlor-5-nitrobenzoyl)-3-(isopropylidenhydrazino)acrylsaeure-ethylester(109308-81-8)
• EPA Substance Registry System: 2-(2,4-Dichlor-5-nitrobenzoyl)-3-(isopropylidenhydrazino)acrylsaeure-ethylester(109308-81-8)

Safety Data

• Hazardous Substances Data: 109308-81-8(Hazardous Substances Data)

Upstream product

• 109308-73-8 ethyl ester of 2-(5-nitro-2,4-dichlorobenzoyl)-3-ethoxyacrylic acid 
• 67-64-1 acetone 

Relevant articles and documents

Cycloaracylation of Enamines,II. - Synthesis of 1-Amino-4-quinolone-3-carboxylic Acids

The 2-benzoyl-3-hydrazinoacrylic esters 3, 11, 17, and 23 are obtained by the reactions of 2-chloro-5-nitrobenzoyl chloride (1) with the enehydrazinocarboxylic esters 2 and 2-benzoyl-3-ethoxyacrylic esters 9 with hydrazine derivatives 10, 16, and 22.After cyclocondensation, the above esters afford 1-aminoquinolonecarboxylic esters 4, 12, 18, and 24, which are hydrolyzed to give the corresponding 1-aminoquinolonecarboxylic acids 5, 13, 19, and 26.The 1-amino-7-haloquinolonecarboxylic acids 13a-f, 19a-f, and 26b react with aliphatic amines to afford 1,7-diaminoquinolonecarboxylic acids 30c-m, which possess a high level of bactericidal activity.