109321-39-3

Basic information

• Product Name: 2-chloro-N-(1,3,4-thiadiazol-2-yl)pyridine-3-carboxamide
• Synonyms: 2-chloro-N-(1,3,4-thiadiazol-2-yl)pyridine-3-carboxamide
• CAS NO: 109321-39-3
• Molecular Formula: C8H5ClN4OS
• Molecular Weight: 240.6695
• Mol File: 109321-39-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-chloro-N-(1,3,4-thiadiazol-2-yl)pyridine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-N-(1,3,4-thiadiazol-2-yl)pyridine-3-carboxamide(109321-39-3)
• EPA Substance Registry System: 2-chloro-N-(1,3,4-thiadiazol-2-yl)pyridine-3-carboxamide(109321-39-3)

Safety Data

• Hazardous Substances Data: 109321-39-3(Hazardous Substances Data)

Upstream product

• 4005-51-0 [1,3,4]Thiadiazol-2-ylamin 
• 49609-84-9 2-Chloronicotinoyl chloride 
• 2942-59-8 2-chloronicotinic acid 

Relevant articles and documents

2-Halobenzoyl chlorides in the synthesis of [1,3,4]thiadiazolo[3,2-a]quinazolin-5-one derivatives

New nitro and sulfonamide derivatives of [1,3,4]thiadiazolo[3,2-a]quinazolin-5-one have been synthesized by cyclocondensation of 1,3,4-thiadiazol-2-amines with 2-halobenzoyl chlorides containing electron-withdrawing substituents in positions 3, 4, and 5. An improved procedure has been proposed for the preparation of intermediate 2-fluoro-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzamides containing a sulfamoyl group in the 5-position via selective acylation of 5-methyl-1,3,4-thiadiazol-2-amine with 5-chlorosulfonyl-2-fluorobenzoyl chloride, followed by sulfonylation of amines.