1093278-52-4

Basic information

• Product Name: 2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine
• Synonyms: 2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine;9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-2-methoxy-9H-purin-6-amine
• CAS NO: 1093278-52-4
• Molecular Formula: C11H14FN5O4
• Molecular Weight: 299.2583632
• Mol File: 1093278-52-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine(1093278-52-4)
• EPA Substance Registry System: 2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine(1093278-52-4)

Safety Data

• Hazardous Substances Data: 1093278-52-4(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 147048-53-1 2'-Deoxy-2,2'-difluoro-adenosine 
• 124-41-4 sodium methylate 
• 157762-25-9 2′-deoxy-2′-fluoro-2-iodoadenosine 
• 114763-45-0 2-iodo-6-methoxy-9-(β-D-ribofuranosyl)purine 
• 150863-85-7 2-iodo-6-methoxy-9-(2-deoxy-2-fluoro-β-D-ribofuranosyl)purine 
• 157762-22-6 2-iodo-6-methoxy-9-(2-O-acetyl-β-D-arabinofuranosyl)purine 
• 157762-19-1 2-iodo-6-methoxy-9-(3,5-O-(tetraisopropyldisiloxane-1,3-diyl)-β-D-ribofuranosyl)purine 
• 157762-24-8 2-iodo-6-methoxy-9-(2-deoxy-2-fluoro-3,5-di-O-(tetrahydro-2-pyranyl)-β-D-ribofuranosyl)purine 
• 157762-23-7 2-iodo-6-methoxy-9-(3,5-di-O-tetrahydropyranyl-β-D-arabinofuranosyl)purine 
• 157762-21-5 2-iodo-6-methoxy-9-(2-O-acetyl-3,5-O-(tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl)purine 
• 157762-20-4 2-iodo-6-methoxy-9-(2-O-triflyl-3,5-O-(tetraisopropyldisiloxane-1,3-diyl)-β-D-ribofuranosyl)purine 
• 700-49-2 2-fluoroadenine 
• 56287-17-3 2'-deoxy-2'-fluorouridine 

Relevant articles and documents

Synthesis and anti-HIV activity of 2-substituted 2'-deoxy-2'- fluoroadenosines

2-Iodo-6-methoxypurine 2'-deoxy-2'-fluororiboside 8 was prepared from 2- iodo-6-methoxypurine riboside 1 in 8 steps. Reaction of 8 with ammonia in methanol gave the 2-iodoadenosine derivative 9 in 69% yield. Treatment of 9 with various nucleophiles gave 2-substituted analogues of 2'-deoxy-2'- fluoroadenosine 10-12. 2'-Deoxy-2,2'-difluoroadenosine 14 was also prepared by the treatment of the quaternary salt 13 with fluoride ion, but similar reactions of 13 with chloride or bromide ion gave the corresponding piperidine congeners 15a,b.