109337-51-1

Basic information

• Product Name: [4-(2-hydroxymethoxycarbonyl)phenyl]benzoate
• Synonyms: [4-(2-hydroxymethoxycarbonyl)phenyl]benzoate
• CAS NO: 109337-51-1
• Molecular Weight: 272.257
• Mol File: 109337-51-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [4-(2-hydroxymethoxycarbonyl)phenyl]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(2-hydroxymethoxycarbonyl)phenyl]benzoate(109337-51-1)
• EPA Substance Registry System: [4-(2-hydroxymethoxycarbonyl)phenyl]benzoate(109337-51-1)

Safety Data

• Hazardous Substances Data: 109337-51-1(Hazardous Substances Data)

Upstream product

• 89-86-1 4-hydroxysalicylic acid 
• 2150-47-2 methyl 2,4-dihydroxybenzoate 
• 98-88-4 benzoyl chloride 

Relevant articles and documents

Physiological activity of Chinese Lichen (Gyrophora esculenta) component, methyl 2,4-dihydroxy-6-methylbenzoate and the related compounds

It was confirmed that there was a higher expression of antioxidant potential in methyl 2,4-dihydroxy-6-methylbenzoate (orsellinic acid methyl ester) (2), which was isolated from methanol extract oil of Chinese lichen Gyrophora esculenta rather than from commercialized ascorbic acid. Taking this into account, 4 types of compounds-(4-7) which are known to be related to compound (2)-have been synthesized by using 2,4-dihydroxy benzoic acid (3) as starting material. After that, some physiological activity tests on these compounds have been conducted in the following aspects: antioxidant potential, cytotoxicity, cytokine suppressant effect and histamine liberation inhibition and the effects have been evaluated, respectively. The result shows that (2) and methyl 2,4-dihydroxybenzoate (4) showed high radical expression in both antioxidant potential and histamine liberation inhibition. It was also found that none of these compounds expresses cytotoxicity.

Methods of protection against emesis in mammals by administration of a heterocyclic benzamide

The heterocyclic benzamides of this invention are particularly effective for the treatment of emesis in mammals. For example, when they are administered to dogs in relatively small dosage, they afford 100% protection against vomiting. They are also non-toxic in dosages for effecting complete control of vomiting.