1093878-13-7

Basic information

• Product Name: 5-bromo-1,3-difluoro-2-(2-methoxyvinyl)benzene
• Synonyms: 5-bromo-1,3-difluoro-2-(2-methoxyvinyl)benzene
• CAS NO: 1093878-13-7
• Molecular Weight: 249.055
• Mol File: 1093878-13-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-bromo-1,3-difluoro-2-(2-methoxyvinyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-1,3-difluoro-2-(2-methoxyvinyl)benzene(1093878-13-7)
• EPA Substance Registry System: 5-bromo-1,3-difluoro-2-(2-methoxyvinyl)benzene(1093878-13-7)

Safety Data

• Hazardous Substances Data: 1093878-13-7(Hazardous Substances Data)

Upstream product

• 461-96-1 3,5-difluorobromobenzene 
• 537013-51-7 4-bromo-2,6-difluorobenzaldehyde 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 

Downstream Products

• 1093878-14-8 2-(3,5-difluoro-4-(2-methoxyvinyl)phenyl)propan-2-ol 
• 1093878-15-9 (2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl)acetaldehyde 
• 1093878-16-0 2-amino-5-(2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl)thiophene-3-carboxamide 
• 1201924-05-1 5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[6-(2-hydroxyethyl)-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-2-yl]amino}thiophene-3-carboxamide 

Relevant articles and documents

NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF

The invention provides compounds for inhibiting glucosylceramidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds.

INHIBITORS OF JANUS KINASES

The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3, TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.