109459-35-0

Basic information

• Product Name: methyl (R)-2-phenyl-2-((trimethylsilyl)oxy)acetate
• Synonyms: methyl (R)-2-phenyl-2-((trimethylsilyl)oxy)acetate
• CAS NO: 109459-35-0
• Molecular Weight: 238.359
• Mol File: 109459-35-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (R)-2-phenyl-2-((trimethylsilyl)oxy)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (R)-2-phenyl-2-((trimethylsilyl)oxy)acetate(109459-35-0)
• EPA Substance Registry System: methyl (R)-2-phenyl-2-((trimethylsilyl)oxy)acetate(109459-35-0)

Safety Data

• Hazardous Substances Data: 109459-35-0(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 20698-91-3 (R)-methyl mandelate 

Downstream Products

• 124649-67-8 methyl (2S,3R)-3-phenyl-2,3-dihydroxypropanoate 
• 130796-32-6 (4S,5R)-trans-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-carbaldehyde 
• 130718-77-3 (4R,5R)-cis-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-carbaldehyde 
• 130796-35-9 (4S,5R)-trans-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-carboxylic acid 
• 130718-78-4 (4R,5R)-cis-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-carboxylic acid 
• 130796-40-6 (2R,3R)-2,3-dihydroxy-3-phenylpropanoic acid methyl ester 
• 130796-37-1 (4S,5R)-2,2-Dimethyl-5-phenyl-[1,3]dioxolane-4-carboxylic acid (S)-1-methyl-heptyl ester 
• 130718-79-5 (4R,5R)-2,2-Dimethyl-5-phenyl-[1,3]dioxolane-4-carboxylic acid (S)-1-methyl-heptyl ester 
• 130718-71-7 erythro (2R,3R)-3-phenyl-1,1-bis(p-tolylthio)propane-2,3-diol 
• 130718-73-9 threo (2S,3R)-3-phenyl-1,1-bis(p-tolylthio)propane-2,3-diol 
• 130718-68-2 (R)-3-hydroxy-3-phenyl-1,1-bis(p-tolylthio)propan-2-one 
• 130796-29-1 (4S,5R)-trans-4--2,2-dimethyl-5-phenyl-1,3-dioxolan 
• 130718-75-1 (4R,5R)-cis-4--2,2-dimethyl-5-phenyl-1,3-dioxolan 
• 109459-40-7 Cyclohexane-1,2-dicarboxylic acid 1-((R)-methoxycarbonyl-phenyl-methyl) ester 2-methyl ester 

Relevant articles and documents

Synthesis of Enantiomerically Pure α-Hydroxyaldehydes from the Corresponding α-Hydroxycarboxylic acids: Novel Substrates for Escherichia coli Transketolase

Enantiomerically pure (R)-α-hydroxyaldehydes (>95percent ee) are prepared from the corresponding α-hydroxyesters by silyl protection, reduction with diisobutylaluminium hydride, and finally deprotection under acidic conditions; subsequent coupling of these aldehydes with lithium hydroxypyruvate, catalysed by Escherichia coli transketolase, leads to novel optically pure triols.