109623-95-2Relevant articles and documents
Phenoxy-substituted beta-carboline derivatives, their production and their use as drugs
-
, (2008/06/13)
Phenoxy-substituted beta-carbolines of the formula I STR1 X is COOR 3, CONHC 1-3 -alkyl or oxadiazolyl of the formula STR2 R 2 is H, lower alkyl or cycloalkyl, R 3 is lower alkyl,R 4 is hydrogen, lower alkyl or lower alkoxyalkyl,R 1 is hydrogen, halogen, lower alkyl, lower alkoxy, acyl, phenyl, C 2-5 alkylenedioxy, trifluoromethyl, nitrilo, nitro, lower alkoxycarbonyl, azido, SO 2 R 6, SO 2 NR 7 R 8, or NR 9 R 10,R 6 is lower alkyl,R 7 and R 8 independently are lower alkyl or together with the nitrogen atom form a hetero ring,R 9 and R 10 independently are hydrogen, lower alkyl, acyl or together with the nitrogen atom form a hetero ring system,with the proviso that X is not COOEt, if STR3 is 5-phenoxy and R 4 is methyl or STR4 is 6-(4-methoxyphenoxy) and R 4 is methoxymethyl have valuable pharmacological properties.