109660-11-9

Basic information

• Product Name: 4,4-dimethyl-2-(naphthalen-2-yl)-4,5-dihydrooxazole
• Synonyms: 4,4-dimethyl-2-(naphthalen-2-yl)-4,5-dihydrooxazole
• CAS NO: 109660-11-9
• Molecular Weight: 225.29
• Mol File: 109660-11-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4,4-dimethyl-2-(naphthalen-2-yl)-4,5-dihydrooxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-dimethyl-2-(naphthalen-2-yl)-4,5-dihydrooxazole(109660-11-9)
• EPA Substance Registry System: 4,4-dimethyl-2-(naphthalen-2-yl)-4,5-dihydrooxazole(109660-11-9)

Safety Data

• Hazardous Substances Data: 109660-11-9(Hazardous Substances Data)

Upstream product

• 4294-57-9 para-methylphenylmagnesium bromide 
• 153683-84-2 4,4-dimethyl-2-<1-(benzylsulfinyl)naphthalen-2-yl>-4,5-dihydrooxazole 
• 153683-83-1 4,4-dimethyl-2-<1-(phenylsulfinyl)naphthalen-2-yl>-4,5-dihydrooxazole 
• 153683-85-3 2-<1-<(4-chlorobenzyl)sulfinyl>naphthalen-2-yl>-4,4-dimethyl-4,5-dihydrooxazole 
• 100-58-3 phenylmagnesium bromide 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 117053-23-3 1-phenyl-2-(4,4-dimethyl-2-oxazolinyl)-1,4-dihydronaphthalene 
• 85678-97-3 4,4-dimethyl-2-(1-phenylnaphthalen-2-yl)-4,5-dihydrooxazole 
• 34968-76-8 5-(4-chloro-phenyl)-2,5-dihydro-3H-benzo[f]imidazo[2,1-a]isoindol-5-ol 
• 113698-36-5 Benazoline 
• 1592-38-7 2-Naphthalenemethanol 

Relevant articles and documents

Atropisomer-selective ligand-coupling reactions of sulfoxides. X-Ray molecular and crystal structures for 2-(thiophen-3-yl>amino)-2-methylpropan-1-ol, 2-(2-hydroxy-1,1-dimethylethyl)-2,3-dihydronaphthoisothiazol-3-one and (R)-(+)-2-bromo-1-(tert...

1-(Alkyl- or aryl-sulfinyl)naphthalenes activated by electron-withdrawing substituents at the 2-position undergo substitution reactions on treatment with Grignard reagents.Evidence suggesting that these transformations proceed through ligand-coupling reactions of ?-sulfuranes is presented.The ligand-coupling reaction of homochiral sulfoxides with 1-naphthylmagnesium bromide furnishes atropisomeric 1,1'-binaphthyls in 60-95percent ee.Single-crystal X-ray structure determinations have been carried out on 2-(thiophen-3-yl>amino)-2-methylpropan-1-ol 18 and 2-(2-hydroxy-1,1-dimethylethyl)-2,3-dihydronaphthoisothiazol-3-one 22, compounds formed through intramolecular nucleophilic and electrophilic attack, respectively, on a neighbouring oxazoline group.The absolute configuration of (R)-(+)-1-(tert-butylsulfinyl)naphthalene 27 was determined by a single-crystal X-ray study of the 2-bromo-derivative 28.