109702-85-4Relevant articles and documents
Mild and highly efficient method for the synthesis of 2-arylbenzimidazoles and 2-arylbenzothiazoles
Bahrami, Kiumars,Mehdi Khodaei,Naali, Fardin
, p. 6835 - 6837 (2008/12/22)
(Chemical Equation Presented) A new, convenient method for the syntheses of 2-substituted benzimidazole and benzothizole is described. Short reaction times, large-scale synthesis, easy and quick isolation of the products, excellent chemoselectivity, and excellent yields are the main advantages of this procedure.
H2O2/HCI as a new and efficient system for synthesis of 2-substituted benzimidazoles
Bahrami, Kiumars,Khodaei, Mohammad M.,Kavianinia, Iman
, p. 783 - 784 (2007/10/03)
The system, H2O2/HCI, oxidises carbon-nitrogen bonds for the synthesis of benzimidazoles from aldehydes and diamines in water at 100°C. Both aryl aldehydes bearing electron-donating and electron-withdrawing substituents afforded desired benzimidazoles in excellent yields. This procedure is also applicable to substituted o-phenylenediamines, which produced 2-phenylbenzimidazoles smoothly in excellent yields. The simplicity of the system, the use of water as the solvent, large-scale synthesis and easy work-up are main advantages of this procedure.