1097104-02-3Relevant articles and documents
Synthesis, Radiosynthesis, and Biological evaluation of carbon-11 and fluorine-18 labeled reboxetine analogues: Potential positron emission tomography radioligands for in vivo imaging of the norepinephrine transporter
Zeng, Fanxing,Mun, Jiyoung,Jarkas, Nachwa,Stehouwer, Jeffrey S.,Voll, Ronald J.,Tamagnan, Gilles D.,Howell, Leonard,Votaw, John R.,Kilts, Clinton D.,Nemeroff, Charles B.,Goodman, Mark M.
experimental part, p. 62 - 73 (2009/09/29)
Reboxetine analogues with methyl and fluoroalkyl substituents at position 2 of the phenoxy ring 1-4 were synthesized. In vitro competition binding with [3H]nisoxetine demonstrated that 1-4 have a high affinity for the norepinephrine transporter