109936-21-2

Basic information

• Product Name: 2-(4-CHLOROPHENYL)-1,1-DIPHENYLETHANOL
• Synonyms: 4-CHLOROBENZYL DIPHENYL CARBINOL;2-(4-CHLOROPHENYL)-1,1-DIPHENYLETHANOL;4-Chlorobenzyl diphenyl carbinol~Clox-H~H-clox;Clox-H;H-clox;2-(4-CHLOROPHENYL)-1,1-DIPHENYLETHANOL 94%
• CAS NO: 109936-21-2
• Molecular Formula: C₂₀H₁₇ClO
• Molecular Weight: 308.8
• Product Categories: Benzhydrols, Benzyl & Special Alcohols
• Mol File: 109936-21-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 116 °C
• Boiling Point: 423.5°C at 760 mmHg
• Flash Point: 209.9°C
• Appearance: /
• Density: 1.204g/cm³
• Vapor Pressure: 6.28E-08mmHg at 25°C
• Refractive Index: 1.625
• PKA: 13.16±0.29(Predicted)
• CAS DataBase Reference: 2-(4-CHLOROPHENYL)-1,1-DIPHENYLETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-CHLOROPHENYL)-1,1-DIPHENYLETHANOL(109936-21-2)
• EPA Substance Registry System: 2-(4-CHLOROPHENYL)-1,1-DIPHENYLETHANOL(109936-21-2)

Safety Data

• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.
• HazardClass: IRRITANT
• Hazardous Substances Data: 109936-21-2(Hazardous Substances Data)

Usage

General Description

2-(4-CHLOROPHENYL)-1,1-DIPHENYLETHANOL is a chemical compound with the molecular formula C20H17ClO. It is a white crystalline solid with a molecular weight of 312.794 g/mol. 2-(4-CHLOROPHENYL)-1,1-DIPHENYLETHANOL is classified as a substituted phenyl ethyl alcohol and is commonly used in the synthesis of various pharmaceuticals and organic compounds. It has also been studied for its potential use as an anti-inflammatory and analgesic agent. Additionally, it has been investigated for its biological activity and potential therapeutic applications. Due to its diverse range of potential uses, 2-(4-CHLOROPHENYL)-1,1-DIPHENYLETHANOL is of interest to researchers in the fields of medicinal chemistry, pharmacology, and organic synthesis.

InChI:InChI=1/C20H17ClO/c21-19-13-11-16(12-14-19)15-20(22,17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-14,22H,15H2

Upstream product

• 119-61-9 benzophenone 
• 874-72-6 4-chlorobenzylmagnesium chloride 
• 622-95-7 4-chlorobenzyl bromide 
• 530-48-3 1,1-Diphenylethylene 
• 673-41-6 p-chlorobenzenediazonium tetrafluoroborate 
• 52449-43-1 (4-chloro-phenyl)-acetic acid methyl ester 
• 100-58-3 phenylmagnesium bromide 
• 1878-66-6 4-chlorophenylacetic Acid 

Downstream Products

• 1229-73-8 (2-(4-chlorophenyl)ethene-1,1-diyl)dibenzene 
• 108667-89-6 2-bromo-2-(4-chloro-phenyl)-1,1-diphenyl-ethanol 
• 796-13-4 1-bromo-1-(4-chloro-phenyl)-2,2-diphenyl-ethene 
• 22021-10-9 1-(p-Chlor-phenyl>-2,2-diphenyl-1-iod-aethylen 
• 1394239-97-4 (2R)-2-amino-3-((2-(4-chlorophenyl)-1,1-diphenylethyl)sulfanyl)propanoic acid 

Relevant articles and documents

Visible Light Promoted, Catalyst-Free Radical Carbohydroxylation and Carboetherification under Mild Biomimetic Conditions

Metal and catalyst-free carbohydroxylations and carboetherifications at room temperature have been achieved by a combination of beneficial factors including high aryl diazonium concentration and visible light irradiation. The acceleration of the reaction by visible light irradiation is particularly remarkable against the background that neither the aryldiazonium salt nor the alkene show absorptions in the respective range of wavelength. These observations point to weak charge transfer interactions between diazonium salt and alkene, which are nevertheless able to considerably influence the reaction course. As highly promising perspective, many more aryldiazonium-based radical arylations might benefit from simple light irradiation without requiring a photocatalyst or particular additive.

Thermally Induced Carbohydroxylation of Styrenes with Aryldiazonium Salts

The radical carbohydroxylation of styrenes with aryldiazonium salts has been achieved under mild thermal conditions. A broad range of aryldiazonium salts was tolerated, and the reaction principle based on a radical–polar crossover mechanism could be exten