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109938-55-8

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109938-55-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 109938-55-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,9,3 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 109938-55:
(8*1)+(7*0)+(6*9)+(5*9)+(4*3)+(3*8)+(2*5)+(1*5)=158
158 % 10 = 8
So 109938-55-8 is a valid CAS Registry Number.

109938-55-8Relevant articles and documents

Linear Relationship between 13C NMR Chemical Shifts and the Bending of sp-Carbon Chains

Kreuzahler, Mathis,Adam, Abdulselam,Haberhauer, Gebhard

, p. 12689 - 12693 (2019/07/18)

Polyynes show a strictly linear relationship between the energy impact and the bending of the polyyne chain. The energy, which is necessary to bend the acetylenic chain, decreases with the increasing number of acetylene units. A deviation from linearity i

Influence of some novel N-substituted azoles and pyridines on rat hepatic CYP3A activity

Slama, James T.,Hancock, Julie L.,Rho, Taikyun,Sambucetti, Lidia,Bachmann, Kenneth A.

, p. 1881 - 1892 (2008/04/18)

A series of N-substituted heteroaromatic compounds structurally related to clotrimazole was synthesized, and the effects of these compounds on ethosuximide clearance in rats were determined as a measure of their abilities to induce cytochrome P4503A (CYP3A) activity. Ethosuximide clearance and in vitro erythromycin N-demethylase activity were shown to correlate. In this series, imidazole or other related heteroaromatic 'head groups' were linked to triphenylmethane or other phenylmethane derivatives. Within the series, it was found that 1-triphenylmethane-substituted imidazoles elicited the greatest increase in CYP3A activity, and that among the triphenylmethyl-substituted imidazoles, the highest activities were achieved by the substitution of F- or Cl- in either the meta or para position of one of the phenyl rings. Diphenylmethylsubstituted pyridine was effectively devoid of activity. Compounds eliciting the largest increase in CYP3A activity (viz. 1-[(3-fluorophenyl)diphenylmethyl]imidazole, 1-[(4- fluorophenyl)diphenylmethyl]imidazole, and 1-[tri-(4- fluorophenyl)methyl]imidazole) produced little or no increase in ethoxyresorufin O-dealkylase (EROD) activity (i.e. CYP1A), whereas benzylimidazole, which elicited only a small increase in CYP3A activity, produced an almost 9-fold increase in CYP1A activity. For a series of eleven compounds exhibiting a wide range of influence on CYP3A activity, a positive correlation was found between ethosuximide clearance and hepatic CYP3A mRNA levels.

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