110-95-2 Usage
Description
Tetramethyl-1,3-diaminopropane, also known as N,N,N′,N′-Tetramethyl-1,3-propanediamine (TMPDA), is an acyclic tertiary amine. It is characterized by its ability to absorb CO2 when dissolved in an aqueous solution. This unique property makes it a versatile compound with various applications across different industries.
Uses
Used in Chemical Synthesis:
Tetramethyl-1,3-diaminopropane is used as a catalyst for the Baylis-Hillman reaction of cycloalkenones. This reaction is an important method for the synthesis of various organic compounds, and TMPDA enhances the efficiency and selectivity of the process.
Used in Dye Preparation:
In the field of dye chemistry, Tetramethyl-1,3-diaminopropane is utilized in the preparation of homodimeric asymmetric monomethine cyanine dyes during the bisquaternization process. These dyes have applications in various industries, including textiles, printing, and bioimaging.
Used in Coordination Chemistry:
Tetramethyl-1,3-diaminopropane also serves as a ligand (L) for the preparation of dinuclear μ-carbonato-dicopper(II) species. This application is significant in coordination chemistry, where such complexes are studied for their structural properties and potential applications in catalysis and materials science.
Physical Properties:
Tetramethyl-1,3-diaminopropane is a colorless liquid, which makes it suitable for use in various chemical processes without the need for additional purification or color removal steps.
Flammability and Explosibility
Flammable
Check Digit Verification of cas no
The CAS Registry Mumber 110-95-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,1 and 0 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 110-95:
(5*1)+(4*1)+(3*0)+(2*9)+(1*5)=32
32 % 10 = 2
So 110-95-2 is a valid CAS Registry Number.
110-95-2Relevant articles and documents
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Chu,Fuoss
, p. 466 (1951)
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Fragmentation During the Formic Acid/Formaldehyde (Eschweiler-Clarke) Methylation of Polyamines
Alder, Roger W.,Colclough, David,Mowlam, Rodney W.
, p. 7755 - 7758 (1991)
Eschweiler-Clarke methylations of both acyclic and cyclic polyamines can lead to methylation products of fragments of the original polyamine; thus 1,5,9,13-tetra-azatridecane yields 1,1,3,3-tetramethylpropanediamine exclusively and 1,5,9-triazacyclododecane gives 45 percent 1,5,9-trimethyl-1,5,9-triazacyclododecane and 45 percent 2,6,10-trimethyl-2,6,10-triazaundecane.
REDUCTIVE PREPARATION OF TERTIARY DIMETHYLAMINES FROM NITRILES
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Paragraph 0058; 0059, (2017/04/04)
This disclosure describes a low temperature process for the preparation of dimethyl amines from nitriles via reductive amination. In some embodiments, the process proceeds under mild conditions with aqeuous dimethylamine and show an unexpected rate acceleration by the inclusion of an acid addition salt of the dimethylamine.
Low pressure process for manufacture of 3-dimethylaminopropylamine (DMAPA)
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Page 4-5, (2008/06/13)
An improved process for the production of 3-dimethylaminopropylamine in high purity from N,N-dimethylaminopropionitrile utilizing a low pressure hydrogenation process is described. The basic process comprises contacting the nitrile with hydrogen at low pressure in the presence of a catalyst under conditions sufficient to effect the conversion of the nitrile to the primary amine product.
