1100-37-4Relevant articles and documents
A Short synthesis of benzomorphane analgesics (±)-Metazocine and (±)-Phenazocine
Singh, Kamal Nain,Singh, Pushpinder,Sharma, Arvind Kumar,Singh, Paramjit,Kessar, Satinder V.
, p. 3716 - 3720 (2010)
A three step synthesis of (±)-metazocine and (±)-phenazocine starting with 3,4-lutidine is described. The key step involves Lewis acid promoted lithiation/electrophilic substitution reaction of N-alkyl-3,4-dimethyl- 1,2,5,6- tetrahydropyridine. Copyright