1100748-67-1 Usage
Chemical structure
Spiro compound with a 1,9-diazaspiro[5.5]undecane core
The compound has a spiro connection between two rings, with one of the rings being a 1,9-diazaspiro[5.5]undecane.
Carboxylic acid group
Present
The compound contains a carboxylic acid functional group, which contributes to its reactivity and properties.
Phenylmethyl group
Attached to the core structure
A phenylmethyl (or benzyl) group is attached to the core structure, providing additional aromatic character and potential points for further chemical reactions.
1,1-Dimethylethyl ester moiety
Present
The carboxylic acid group is esterified with a 1,1-dimethylethyl (tert-butyl) group, making the compound a volatile liquid at room temperature.
Physical state
Volatile liquid at room temperature
Due to the 1,1-dimethylethyl ester moiety, the compound is a liquid that easily evaporates.
Applications
Pharmaceutical manufacturing, organic synthesis, flavoring agent, and fragrance
The compound is used in various industries, including pharmaceuticals, organic synthesis, food, and cosmetics.
Potential applications
Medicinal chemistry
Due to its unique chemical structure and potential biological activities, spirodecanone may have future applications in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1100748-67-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,0,0,7,4 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1100748-67:
(9*1)+(8*1)+(7*0)+(6*0)+(5*7)+(4*4)+(3*8)+(2*6)+(1*7)=111
111 % 10 = 1
So 1100748-67-1 is a valid CAS Registry Number.
1100748-67-1Relevant articles and documents
Synthesis of four novel natural product inspired scaffolds for drug discovery
Jenkins, Ian D.,Lacrampe, Fabienne,Ripper, Justin,Alcaraz, Lilian,Van Le, Phuc,Nikolakopoulos, George,De Leone, Priscila Almeida,White, Rodney H.,Quinn, Ronald J.
experimental part, p. 1304 - 1313 (2009/07/04)
Inspired by the novel spiro structures of a number of bioactive natural products such as the histrionicotoxins, a series of novel spiro scaffolds have been designed and robust syntheses developed. The scaffolds are ready-to-use building blocks and can be easily prepared on a 5-20 g scale. They contain two amino groups (one Boc-protected) and have been designed for ease of conversion to a lead generation library, using either amide formation or reductive amination procedures. The synthesis of the 1,9-diazaspiro[5.5]undecane and 3,7-diazaspiro[5.6]dodecane ring systems was achieved using RCM as the key step. A simple workup procedure is reported for the removal of highly colored ruthenium residues. The synthesis of the 1,8-diazaspiro[4.5]decane scaffold has been achieved using a bromine-mediated 5-endo cyclization of the corresponding 4-aminobutene intermediate under acidic conditions. This is the first example of this type of cyclization to be reported. A novel mechanism involving a bromine transfer reaction from an initially formed bromonium ion to a neighboring nitrogen atom is suggested as the reason for the failure of this type of reaction under "normal" bromination conditions. An unusual rearrangement of a 1-acyl-1,9-diazaspiro[5.5]undecane to the corresponding 9-acyl-1,9-diazaspiro[5.5]undecane is reported.
