1100995-52-5

Basic information

• Product Name: 4'-{[2-n-propyl-4-methyl-6-(1-methylbenzoimidazol-2-yl)benzoimidazol-1-yl]methyl}-2-(5-chloro-1-(triphenylmethyl)-imidazole-2-yl)biphenyl
• Synonyms: 4'-{[2-n-propyl-4-methyl-6-(1-methylbenzoimidazol-2-yl)benzoimidazol-1-yl]methyl}-2-(5-chloro-1-(triphenylmethyl)-imidazole-2-yl)biphenyl
• CAS NO: 1100995-52-5
• Molecular Weight: 813.444
• Mol File: 1100995-52-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4'-{[2-n-propyl-4-methyl-6-(1-methylbenzoimidazol-2-yl)benzoimidazol-1-yl]methyl}-2-(5-chloro-1-(triphenylmethyl)-imidazole-2-yl)biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-{[2-n-propyl-4-methyl-6-(1-methylbenzoimidazol-2-yl)benzoimidazol-1-yl]methyl}-2-(5-chloro-1-(triphenylmethyl)-imidazole-2-yl)biphenyl(1100995-52-5)
• EPA Substance Registry System: 4'-{[2-n-propyl-4-methyl-6-(1-methylbenzoimidazol-2-yl)benzoimidazol-1-yl]methyl}-2-(5-chloro-1-(triphenylmethyl)-imidazole-2-yl)biphenyl(1100995-52-5)

Safety Data

• Hazardous Substances Data: 1100995-52-5(Hazardous Substances Data)

Upstream product

• 1100995-50-3 1-triphenylmethyl-2-(4'-bromomethylbiphenyl-2-yl)-5-chloro-1H-imidazole 
• 152628-02-9 2-n-propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)benzimidazole 

Downstream Products

• 1100995-33-2 4'-[[4-methyl-6-(1-methyl-benzoimidazol-2-yl)-2-propyl-benzoimidazol]-1-yl]methyl-2-(5-chloroimidazole-2-yl)-biphenyl 

Relevant articles and documents

Synthesis and biological activities of novel nonpeptide angiotensin II receptor antagonists based on benzimidazole derivatives bearing a heterocyclic ring

A series of benzimidazole derivatives bearing a heterocyclic ring imidazole (1), 5-chloroimidazole (2), 1,2,4-triazol (3), and imidazoline (4) were synthesized and evaluated for angiotensin II antagonistic activities. The synthetic compounds 1-4 were biologically evaluated in vitro using an AT1 receptor binding assay, where compounds 1 and 3 provided weak binding affinity, compound 2 showed moderate binding affinity, and compound 4 showed good binding affinity. Moreover, compound 4 was found to be almost equipotent with telmisartan in vivo biological evaluation study.