1101173-94-7

Basic information

• Product Name: tert-Butyl (3-broMo-1,2,4-thiadiazol-5-yl)carbaMate
• Synonyms: tert-Butyl (5-broMo-1,3,4-thiadiazol-2-yl)carbaMate;tert-Butyl (3-broMo-1,2,4-thiadiazol-5-yl)carbaMate
• CAS NO: 1101173-94-7
• Molecular Formula: C₇H₁₀BrN₃O₂S
• Molecular Weight: 280.1422
• Mol File: 1101173-94-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: tert-Butyl (3-broMo-1,2,4-thiadiazol-5-yl)carbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl (3-broMo-1,2,4-thiadiazol-5-yl)carbaMate(1101173-94-7)
• EPA Substance Registry System: tert-Butyl (3-broMo-1,2,4-thiadiazol-5-yl)carbaMate(1101173-94-7)

Safety Data

• Hazardous Substances Data: 1101173-94-7(Hazardous Substances Data)

Usage

General Description

Tert-Butyl (3-bromo-1,2,4-thiadiazol-5-yl)carbamate is a chemical compound with the molecular formula C8H13BrN3O2S. It is a carbamate derivative with a tert-butyl group attached to a 3-bromo-1,2,4-thiadiazol-5-yl ring. tert-Butyl (3-broMo-1,2,4-thiadiazol-5-yl)carbaMate has potential applications in the field of medicinal chemistry as it exhibits biological activity and could be used in the synthesis of pharmaceuticals. Its unique structure and properties make it a valuable tool for scientists and researchers studying the interactions of carbamate compounds with biological systems.

Upstream product

• 1101173-93-6 3-bromo-5-amino-1,2,4-thiadiazole 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1101173-95-8 tert-butyl 3-(4-(methylsulfonyl)phenyl)-1,2,4-thiadiazol-5-ylcarbamate 
• 1198321-19-5 C₁₅H₁₆N₆O₂S 
• 1198321-21-9 C₁₄H₁₇N₃O₂S 
• 1198321-18-4 tert-butyl 3-(4-(N-tert-butylsulfamoyl)phenyl)-1,2,4-thiadiazol-5-ylcarbamate 
• 1198321-20-8 C₁₅H₁₈N₄O₃S 
• 1198321-17-3 C₁₄H₁₈N₄O₄S₂ 
• 1198321-16-2 C₁₃H₁₅N₃O₂S 
• 1401349-80-1 tert-butyl (3-(3-iodo-1-tosyl-1H-indol-5-yl)-1,2,4-thiadiazol-5-yl)carbamate 
• 1401349-81-2 tert-butyl (3-(3-(6-isopropoxypyridin-2-yl)-1-tosyl-1H-indol-5-yl)-1,2,4-thiadiazol-5-yl)carbamate 
• 1401349-83-4 tert-butyl (3-(3-(6-(isopropylamino)pyrazin-2-yl)-1-tosyl-1H-indol-5-yl)-1,2,4-thiadiazol-5-yl)carbamate 

Relevant articles and documents

Pharmacological evaluation of novel (6-aminopyridin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl) methanone derivatives as TRPV4 antagonists for the treatment of pain

A novel series of (6-aminopyridin-3-yl)(4-(pyridin-2-yl)piperazin-1-yl) methanone derivatives were identified as selective transient receptor potential vanilloid 4 (TRPV4) channel antagonist and showed analgesic effect in Freund's Complete Adjuvant (FCA) induced mechanical hyperalgesia model in guinea pig and rat. Modification of right part based on the compound 16d which was disclosed in our previous communication led to the identification of compound 26i as a flagship compound. In this paper, we described the details about design, synthesis and structure-activity relationship (SAR) analysis at right and left part of these derivatives (Fig. 1).

AZOLE COMPOUNDS AS PIM INHIBITORS

The invention relates to bicyclic compounds of formulas I and Ia, and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of Pim-1 and/or Pim-2, and/or Pim-3 protein kinase activity or enzyme function. In still further em

DERIVATlVES OF UREA AND RELATED DIAMINES, METHODS FOR THEIR MANUFACTURE AND USES THEREFOR

The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders related to the function of the calcium sensing receptor. The invention also relates to processes for making such compounds and to intermediates useful in these processes