110187-19-4Relevant articles and documents
Total Synthesis of Ostopanic Acid, a Plant Cytotoxin, via Cyclopropanation of 2-n-Hexylfuran
Sheu, Jyh-Horng,Yen, Ching-Fen,Huang, Hua-Chih,Hong, Yen-Long Vincent
, p. 5126 - 5128 (1989)
The cyclopropanation of 2-n-hexylfuran with ethyl 8-diazo-7-oxooctanoate catalyzed by dirhodium tetraacetate as a key step for synthesis of ostopanic acid is reported.This reaction allowed the preparation of ethyl ostopanate (5) and its unstable regioisomer (10) in 58percent yield.Exposure of the mixture to a catalytic amount of iodine in dichloromethane afforded pure ethyl ostopanate, which was converted to the target compound in two steps.
A facile and stereoselective synthesis of dienediones and 6-oxo-2,4-dienoic esters
Guo, Cheng,Lu, Xiyan
, p. 3659 - 3662 (1992)
Ostopanic acid and ethyl 6-oxodocosa-2,4-dienoate were synthesized by a short route based on the palladium catalyzed isomerization of ynone and ynoic ester, respectively, using pent-4-ynal as a starting material.
Reinvestigation on the Catalytic Isomerisation of Carbon-Carbon Triple Bonds
Guo, Cheng,Lu, Xiyan
, p. 1921 - 1924 (2007/10/02)
Based on the discovery that phosphines could catalyse the isomerisation of triple bonds, the isomerisation of acetylenic derivatives was differentiated into two types: phosphine-catalysed and transition metal-catalysed.