110236-78-7

Basic information

• Product Name: 5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid
• CAS NO: 110236-78-7
• Molecular Formula: C₁₇H₁₈F₂N₄O₃
• Molecular Weight: 364.3466
• Mol File: 110236-78-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 652.7°C at 760 mmHg
• Flash Point: 348.5°C
• Density: 1.562g/cm³
• Vapor Pressure: 6.35E-18mmHg at 25°C
• Refractive Index: 1.673
• CAS DataBase Reference: 5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid(110236-78-7)
• EPA Substance Registry System: 5-amino-1-cyclopropyl-6,8-difluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid(110236-78-7)

Safety Data

• Hazardous Substances Data: 110236-78-7(Hazardous Substances Data)

Upstream product

• 110-85-0 piperazine 
• 103772-14-1 5-Amino-1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid 
• 103772-12-9 ethyl 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-5-nitro-4-oxo-3-quinolinecarboxylate 
• 107564-02-3 1-cyclopropyl-5,6,7,8-tetrafluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid,ethyl ester 
• 103772-13-0 ethyl 5-amino-1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate 
• 110872-04-3 ethyl 5-(benzylamino)-1-cyclopropyl-6,7,8-trifluoro-4(1H)-oxoquinoline-3-carboxylate 

Relevant articles and documents

Oxo quinoline derivatives

A quinoline derivative of the formula STR1 wherein Z is an amino group or a halogen atom, and R1, R2 and R3 are the same or different and each represents a hydrogen atom or a lower alkyl group having 1 to 5 carbon atoms, and an ester thereof and a salt of the derivative or the ester and processes for preparation thereof. These compounds show excellent antibacterial activity and are useful as antibacterial agents.

5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents

Novel 7-piperazine derivatives of 5-amino- and 5-hydroxy-1-cyclopropyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections.

5-amino-6,8-difluoroquinolones as antibacterial agents

Novel 7-piperazino and 7-N-methylpiperazino derivatives of 5-amino-1-cyclopropyl-6,8-dihydro-1,4-dihydro-4-oxoquinoline-3-carboxylic acids as antibacterial agents are described as well as methods for their manaufacture, formulation, and use in treating bacterial infections.