110271-93-7Relevant articles and documents
Synthesis of benzyl hydrazine derivatives: Via amination of benzylic C(sp3)-H bonds with dialkyl azodicarboxylates
Samzadeh-Kermani
, p. 4766 - 4772 (2018)
A novel synthesis of benzyl hydrazines through oxidative amination of benzylic C-H bonds has been developed. The resulting aminated products are accessed directly from the reaction of alkylarenes with dialkyl/diphenyl azodicarboxylates using Cu2O/Phen as the catalytic system. The reaction proceeded smoothly and a decent range of N-substituted hydrazides was synthesized in acceptable to good yields. Both primary and secondary sp3 C-H sources afford only monoamination products.
Reactions of α-Hydroxy Carbonyl Compounds with Azodicarboxylates and Triphenylphosphine: Synthesis of α-N-Hydroxy Amino Acid Derivatives
Kolasa, Teodozyj,Miller, Marvin J.
, p. 4978 - 4984 (2007/10/02)
Reaction of aliphatic α-hydroxy esters with azodicarboxylates and triphenylphosphine in the presence of either CbzNHOCH2Ph or trOCNHOCH2Ph provides a direct route to protected α-N-hydroxy amino acids.Similar reactions with aromatic α-hydroxy carbonyl compounds and derivatives result in predominate oxidation to the corresponding α-oxo carbonyl derivatives.