110407-24-4

Basic information

• Product Name: 1-Piperazinehexanamide, 4-[(4-chlorophenyl)phenylmethyl]-N-(6-methoxy-4-methyl-8-quinolinyl)-
• CAS NO: 110407-24-4
• Molecular Formula: C34H39ClN4O2
• Molecular Weight: 571.162
• Mol File: 110407-24-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Piperazinehexanamide, 4-[(4-chlorophenyl)phenylmethyl]-N-(6-methoxy-4-methyl-8-quinolinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazinehexanamide, 4-[(4-chlorophenyl)phenylmethyl]-N-(6-methoxy-4-methyl-8-quinolinyl)-(110407-24-4)
• EPA Substance Registry System: 1-Piperazinehexanamide, 4-[(4-chlorophenyl)phenylmethyl]-N-(6-methoxy-4-methyl-8-quinolinyl)-(110407-24-4)

Safety Data

• Hazardous Substances Data: 110407-24-4(Hazardous Substances Data)

Upstream product

• 303-26-4 N-(4-chlorobenzhydryl)piperazine 
• 75464-75-4 6-bromo-N-(6-methoxy-4-methyl-8-quinolinyl)-hexanamide 
• 22809-37-6 6-bromohexanoyl chloride 
• 57514-21-3 8-amino-6-methoxy-4-methylquinoline 

Relevant articles and documents

Anti-leishmanial lepidine derivatives

The subject 8-[6-(N-heterocyclic-substituted)hexylamino]-6-methoxy lepidineerivatives have the formula: STR1 wherein Z represents methyl or, together with the two contiguous carbon atoms, the benzo moiety of a benzopiperazinyl derivative when Y is --N(R')--, n is an integer from 0 to 2; Y represents --O--, --S--, --S(O)--, --S(O)2 --, and --N(R')--; R' represents hydrogen, alkyl, lower alkyl, R" substituted lower alkyl, cycloalkyl, aryl, sulfonyl, saturated 1,4-diazepinyl, lower alkyl N-cyanocarboximidothioate, or --C(O)R'"; R" represents at least one of hydroxy, alkoxy, aralkoxy, amino, lower alkyl substituted amino, phenyl, halogenated phenyl, or sufonyl; and R'" represents lower alkyl, alkoxy, aralkoxy, amino, lower alkyl substituted amino or aryl substituted amino; and pharmaceutically acceptable salts thereof. These derivatives afford improvement in means for the chemotherapy of leishmaniasis when administered parenterally or orally to infected animals.