110451-11-1

Basic information

• Product Name: (1'S)-1',2'-bis(methoxycarbonyl)ethyl 3-oxo-6-tetrahydropyran-2-yloxyhexanoate
• Synonyms: (1'S)-1',2'-bis(methoxycarbonyl)ethyl 3-oxo-6-tetrahydropyran-2-yloxyhexanoate
• CAS NO: 110451-11-1
• Molecular Weight: 374.388
• Mol File: 110451-11-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1'S)-1',2'-bis(methoxycarbonyl)ethyl 3-oxo-6-tetrahydropyran-2-yloxyhexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (1'S)-1',2'-bis(methoxycarbonyl)ethyl 3-oxo-6-tetrahydropyran-2-yloxyhexanoate(110451-11-1)
• EPA Substance Registry System: (1'S)-1',2'-bis(methoxycarbonyl)ethyl 3-oxo-6-tetrahydropyran-2-yloxyhexanoate(110451-11-1)

Safety Data

• Hazardous Substances Data: 110451-11-1(Hazardous Substances Data)

Upstream product

• 70681-41-3 (R)-dimethyl malate 
• 110451-01-9 S-t-butyl 3-oxo-6-terahydropyran-2-yloxyhexanethioate 

Relevant articles and documents

PREPARATION OF ACYLTETRONIC ACIDS USING t-BUTYL ACETOTHIOACETATE: TOTAL SYNTHESIS OF THE FUNGAL METABOLITES CAROLIC, CARLOSIC, AND CARLIC ACIDS

Dianions generated from S-t-butyl acetothioacetate ( 1 ) were alkylated with a variety of electrophiles at the γ-carbon centre.Treatment of the alkylated products with 2-hydroxy esters in the presence of silver(I) salts gave transesterified acetoacetate derivatives in good yields.These acetoacetates were cyclised efficiently to acyltetronic acid derivatives using tetrabutyl ammonium fluoride in THF solution at room temperature.By an appropriate choice of substituents the total synthesis of the fungal metabolite natural products carlosic, carolic, and carlic acids have been achieved.