110484-40-7Relevant articles and documents
Total Synthesis of Thymosin β4, 3. Conventional Synthesis of the Fragment of Thymosin β4
Link, Peter,Voelter, Wolfgang
, p. 1000 - 1008 (2007/10/02)
As part of our total synthesis of thymosin β4, an optimized synthesis of the C-terminal part of thymosin β4 is described.Side chain functional residues of the tridecapeptide are masked by tert-butyl and the α-amino-acids residues are protected by the Z groups.The fully protected peptide derivative was obtained by WSCI/HOBt coupling of three fragments representing the segments , and . Key words: Thymosin β4; fragment ; peptide; solution synthesis; thymosins.
Solution Synthesis of a Biologically Active Fragment (33-41) of Thymosin β9
Kalbacher, Hubert,Jahan, Meeno,Mihelic, Mirna,Zaman, Fakhar,Voelter, Wolfgang
, p. 249 - 252 (2007/10/02)
The C-terminal fragment 33-41 of thymosin β9 is synthesized by solution synthesis, using the strategy of maximum sidechain protection with acid-labile tert-butyl groups and temporary Nα-benzyloxycarbonyl protection during the elongat