110497-15-9

Basic information

• Product Name: 1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-4-hydroxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione
• Synonyms: 1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-4-hydroxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione
• CAS NO: 110497-15-9
• Molecular Weight: 498.626
• Mol File: 110497-15-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-4-hydroxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-4-hydroxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione(110497-15-9)
• EPA Substance Registry System: 1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-3-fluoro-4-hydroxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione(110497-15-9)

Safety Data

• Hazardous Substances Data: 110497-15-9(Hazardous Substances Data)

Upstream product

• 122799-38-6 1-(2'-deoxy-2'-fluoro-β-D-ribofuranosyl)-5-methyluracil 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 719302-95-1 5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluoro-3'-O-(4-methylphenoxy)thiocarbonyl-5-methyluridine 
• 337980-10-6 5'-O-(tert-butyldiphenylsilyl)-2',3'-dideoxy-2'-β-fluoro-3'-C-(2-phenylethenyl)-5-methyluridine 
• 312934-28-4 5'-O-(tert-butydiphenylsilyl)-2',3'-dideoxy-2'-β-fluoro-3'-C-(iodomethyl)-5-methyluridine 
• 312934-46-6 2',3'-dideoxy-2'-β-fluoro-3'-C-(iodomethyl)-5'-O-(4-methoxytrityl)-5-methyluridine 
• 312934-39-7 2',3'-dideoxy-5'-O-(4,4'-dimethoxytrityl)-2'-β-fluoro-3'-C-(iodomethyl)-5-methyluridine 
• 318246-90-1 5'-O-(tert-butydiphenylsilyl)-2',3'-dideoxy-2'-β-fluoro-3'-C-(hydroxymethyl)-5-methyluridine 

Relevant articles and documents

Synthesis of 2′-Substituted MMI Linked Nucleosidic Dimers: An Optimization Study in Search of High Affinity Oligonucleotides for Use in Antisense Constructs

The synthesis of a series of methylene(methylimino) (MMI) linked oligodeoxyribonucleotide dimers modified at the 2′-position with fluoro and/or methoxy groups and their incorporation into different sequences has been accomplished. From these dimers, bis 2