110522-93-5

Basic information

• Product Name: 5-Benzyl-1-[(2R,3R,4R,5R)-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione
• Synonyms: 5-Benzyl-1-[(2R,3R,4R,5R)-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione
• CAS NO: 110522-93-5
• Molecular Weight: 677.117
• Mol File: 110522-93-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Benzyl-1-[(2R,3R,4R,5R)-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Benzyl-1-[(2R,3R,4R,5R)-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione(110522-93-5)
• EPA Substance Registry System: 5-Benzyl-1-[(2R,3R,4R,5R)-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione(110522-93-5)

Safety Data

• Hazardous Substances Data: 110522-93-5(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 64898-15-3 2',3',5'-tris-O-(tert-butyldimethylsilyl)uridine 

Downstream Products

• 99388-49-5 5-benzyluridine 

Relevant articles and documents

A SIMPLE AND GENERAL ENTRY TO 5-SUBSTITUTED URUDINES BASED ON THE REGIOSELECTIVE LITHIATHION CONTROLLED BY A PROTECTING GROUP IN THE SUGAR MOIETY

Lithiathion of 2',3',5'-tris-O-(tert-butyldimethylsilyl)uridine with sec-BuLi/TMEDA occurs at the C-5 position with a high regioselectivity and subsequent reactions of the resulting C-5 lithiated species with a variety of electrophiles provides a general entry to 5-substituted uridines.