110789-58-7Relevant articles and documents
SYNTHESIS OF 1-SUBSTITUTED 1,2,3,9a-TETRAHYDRO-9H-IMIDAZOINDOL-2-ONES
Shachkus, A. A.,Degutis, Yu. A.
, p. 1198 - 1202 (2007/10/02)
1-R-9,9,9a-Trimethyl-1,2,3,9a-tetrahydro-9H-imidazoindol-2-ones and the corresponding 2-methylene-2,3-dihydroindoles were obtained by the reaction of 2,3,3-trimethyl-3H-indole with a number of N-substituted chloroacetic acid amides and subsequent reaction of the resulting quartenary salts with bases.The kinetics of intramolecular cyclization of 1-(N-alkylcarbamoylethyl)-2-methylene-2,3-dihydroindoles under the influence of acetic acid were studied.Under the influence of strong protic acids 1-R-imidazoindol-2-ones undergo decyclization and are converted to 3H-indolium salts.