1108723-71-2

Basic information

• Product Name: 5-(tert-butyl)-2-((tert-butyldimethylsilyl)oxy)benzaldehyde
• Synonyms: 5-(tert-butyl)-2-((tert-butyldimethylsilyl)oxy)benzaldehyde
• CAS NO: 1108723-71-2
• Molecular Weight: 292.494
• Mol File: 1108723-71-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-(tert-butyl)-2-((tert-butyldimethylsilyl)oxy)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(tert-butyl)-2-((tert-butyldimethylsilyl)oxy)benzaldehyde(1108723-71-2)
• EPA Substance Registry System: 5-(tert-butyl)-2-((tert-butyldimethylsilyl)oxy)benzaldehyde(1108723-71-2)

Safety Data

• Hazardous Substances Data: 1108723-71-2(Hazardous Substances Data)

Upstream product

• 2725-53-3 2-hydroxy-5-t-butylbenzaldehyde 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 98-54-4 para-tert-butylphenol 

Downstream Products

• 1325228-81-6 (E)-2-(4-(5-tert-butyl-2-hydroxyphenyl)but-3-enyl)phenol 
• 1033366-35-6 C₂₀H₂₂O₂ 

Relevant articles and documents

Enantioselective Catalytic [4+1]-Cyclization of ortho-Hydroxy-para-Quinone Methides with Allenoates

The first highly asymmetric catalytic synthesis of densely functionalized dihydrobenzofurans is reported, which starts from ortho-hydroxy-containing para-quinone methides. The reaction relies on an unprecedented formal [4+1]-annulation of these quinone methides with allenoates in the presence of a commercially available chiral phosphine catalyst. The chiral dihydrobenzofurans were obtained as single diastereomers in yields up to 90 % and with enantiomeric ratios up to 95:5.

Development of a Cofilin Inhibitor for the Treatment of Hemorrhagic Brain Injury-Induced Neuroinflammation

Compounds and methods for inhibiting cofilin activity or reducing total cofilin, improving motor deficits, attenuating LPS-induced microglial activation and inflammation, reducing microglial migration and proliferation, reducing TNF-α, reducing NF-κB, and improving motor deficits in a subject are described.

(3-HYDROXY-4-AMINO-BUTAN-2-YL) -3- (2-THIAZOL-2-YL-PYRROLIDINE-1-CARBONYL) BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BETA-SECRETASE INHIBITORS FOR TREATING

The present invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer's disease. (Formula)