110954-03-5Relevant articles and documents
Synthesis of chitosan-la2o3 nanocomposite and its utility as a powerful catalyst in the synthesis of pyridines and pyrazoles
Farghaly, Thoraya A.,Hagar, Mohamed,Jaremko, Mariusz,Khalil, Khaled D.,Riyadh, Sayed M.
, (2021)
Recently, the development of nanocatalysts based on naturally occurring polysaccharides has received a lot of attention. Chitosan (CS), as a biodegradable and biocompatible polysaccharide, is considered to be an excellent template for the design of a hybr
Enaminones as building blocks in organic synthesis: A novel route to polyfunctionally substituted benzonitriles, pyridines, eneylbenzotriazoles and diazepines
Hassanien, Abu Zeid A.,Ghozlan, Said A. S.,Elnagdi, Mohamed H.
, p. 225 - 228 (2007/10/03)
An efficient synthesis of enaminones 1a-c is reported. Compounds 1a-c reacted with diethyl-3-amino-2-cyanopenten-1,5-dicarboxylate (3) to yield the benzonitriles 6. On the other hand, the reaction of 1a-c with 3-amino-2-cyano-2-pentene dinitrile (7) affor
CYCLIZATION OF 2-DICYANOMETHYLENE-1,2-DIHYDROPYRIDINE-3-CARBONITRILES WITH HYDROGEN HALIDES: A RE-EXAMINATION ON THE REGIOSELECTIVITY
Victory, Pedro,Busquets, Nuria,Borrell, Jose I.,Teixido, Jordi,Serra, Blanca,et al.
, p. 1013 - 1022 (2007/10/02)
The cyclization of the title compounds (5a-c) with HCl and HBr has been re-examined.In all cases 5-amino-7-halo-substituted 1,6-naphthyridines (11a-c and 12a-c) were formed independently of the thermal level and the hydrogen halide employed.The structures of 11a-c and 12a-c were unequivocally established by reaction with hydrazine which affforded the corresponding pyrazolonaphthyridines (14a-c).The structure of the methoxy derivatives (15a,c and 16a,c) was assigned by two-dimensional nmr studies.
