111098-96-5

Basic information

• Product Name: (2R,3S,4S,5R)-4-Nitro-1,3,5-triphenyl-pyrrolidine-2-carboxylic acid methyl ester
• Synonyms: (2R,3S,4S,5R)-4-Nitro-1,3,5-triphenyl-pyrrolidine-2-carboxylic acid methyl ester
• CAS NO: 111098-96-5
• Molecular Weight: 402.45
• Mol File: 111098-96-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2R,3S,4S,5R)-4-Nitro-1,3,5-triphenyl-pyrrolidine-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S,4S,5R)-4-Nitro-1,3,5-triphenyl-pyrrolidine-2-carboxylic acid methyl ester(111098-96-5)
• EPA Substance Registry System: (2R,3S,4S,5R)-4-Nitro-1,3,5-triphenyl-pyrrolidine-2-carboxylic acid methyl ester(111098-96-5)

Safety Data

• Hazardous Substances Data: 111098-96-5(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 5153-67-3 nitrostyrene 
• 113436-49-0 (3R,4R,5R)-4-Nitro-1,3,5-triphenyl-pyrrolidine-2,2-dicarboxylic acid dimethyl ester 
• 78733-46-7 methyl (+/-)-phenylglycinate hydrochloride 
• 23284-84-6 N-phenylglycine methyl ester 

Relevant articles and documents

Cycloadditions dipolaires 1,3 aux derives nitres α ethyleniques, acetyleniques potentiels. I. Reaction avec des ylures d'azomethine. Orientation et stereochimie de la cycloaddition

The stereochemistry of the nitroolefins 1 prepared by known methods was unambigously established.Their reactions with azomethine ylides (e.g. 8) was studied and the stereochemistry of the adducts as well.This preliminary work was necessary to substantiate a discussion of structural (pyrrolidines conformational analysis) and mechanistic problems (dipolarophile-azomethine ylide approach and HNO2 elimination from the nitro pyrrolidines).

Stable configuration of Ester-Stabilized Azomethine Ylides. Stabilization of anti-Form by 1,5-Dipolar Interaction and of syn-Form by Hydrogen Bonding

Stable configuration of ester-stabilized azomethine ylides is found to depend upon the substituent on the ylide nitrogen.Thus, N-substituted azomethine ylides derived from N-substituted 2-amino-acetates and carbonyl compounds undergo cycloaddition with ol