111114-09-1

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-[2-(3,4-dimethoxyphenyl)-2-oxoethyl]-
• CAS NO: 111114-09-1
• Molecular Formula: C18H15NO5
• Molecular Weight: 325.321
• Mol File: 111114-09-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-[2-(3,4-dimethoxyphenyl)-2-oxoethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-[2-(3,4-dimethoxyphenyl)-2-oxoethyl]-(111114-09-1)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-[2-(3,4-dimethoxyphenyl)-2-oxoethyl]-(111114-09-1)

Safety Data

• Hazardous Substances Data: 111114-09-1(Hazardous Substances Data)

Upstream product

• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 
• 91-16-7 1,2-dimethoxybenzene 
• 1835-02-5 2-Bromo-1-(3,4-dimethoxyphenyl)ethanone 
• 1074-82-4 potassium phtalimide 
• 4702-13-0 N-phthaloylglycine 
• 26477-09-8 N-2-(3,4-dimethoxyphenyl)ethylphthalimide 
• 85-44-9 phthalic anhydride 
• 155344-84-6 N-<2-(hydroxy)-2-(3,4-dimethoxyphenyl)ethyl>phthalimide 
• 6780-38-7 N-phthaloylglycine chloride 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 

Downstream Products

• 499-61-6 arterenone 
• 871902-52-2 N-(3,4-dimethoxy-phenacyl)-phthalamic acid 
• 217954-75-1 C₁₃H₁₃N₃O₂ 

Relevant articles and documents

Facile methods for the synthesis of 5-aryl and 5-iodo pyrrolo[2,3-d] pyrimidines

An efficient and environmentally benign one-pot method has been developed for the synthesis of 4-amino-5-arylpyrrolo[2,3-d]pyrimidines. Phthalimido acetophenones were reacted with cyanoacetamide to give 2-amino-4-phenyl-1H- pyrrole-3-carboxamides, which were further converted to 5-aryl-3H-pyrrolo[2,3-d] pyrimidin-4-ones. A novel method is also developed for the synthesis of 4-amino-5-iodopyrrolo[2,3-d]pyrimidines.

Ferric Chloride-Catalyzed Acylation of Aromatic Compounds with N-Phthaloyl-α-amino Acyl Chlorides without Racemisation

Reactive aromatic compounds are acylated without racemisation to aryl 1-phthalimidoalkyl ketones 4 in good yields with N-phthaloyl-α-amino acid chlorides in the presence of catalytic amounts (1 to 5 mol-percent) of FeCl3.This new method is especially useful for the synthesis of the pharmacologically interesting alkoxyaryl 1-phthalimidoalkyl ketones 6, 8, 10, and 11, which cannot be prepared in reasonable yields in the presence of other FC catalysts such as AlCl3 or SnCl4.