1111310-87-2Relevant articles and documents
Synthesis of isoindoles via 1,3-dipolar cycloaddition of α-azido carbonyl compounds onto intramolecular alkenes and their conversion into substituted aromatic hydrocarbons
Tong, Benny Meng Kiat,Hui, Benjamin Wei-Qiang,Chua, Sze Hui,Chiba, Shunsuke
supporting information; experimental part, p. 3552 - 3562 (2011/12/04)
α-Azido carbonyl compounds bearing a 2-alkenylaryl moiety in the α-position are found to be promising precursors in the synthesis of isoindoles via 1,3-dipolar cycloaddition of azides to alkenes. Applications of these isoindoles in the preparation of 1,2,3,4-tetrasubstituted naphthalene and 9,10-disubstituted anthracene derivatives were developed via [4+2]-cycloaddition reactions of isoindoles with dimethyl acetylenedicarboxylate and benzynes, respectively, followed by deaminative aromatization. Georg Thieme Verlag Stuttgart.