1111637-77-4

Basic information

• Product Name: 3-(DifluoroMethoxy)-2-Nitropyridine
• Synonyms: 3-(DifluoroMethoxy)-2-Nitropyridine
• CAS NO: 1111637-77-4
• Molecular Formula: C6H4F2N2O3
• Molecular Weight: 190.1043664
• Mol File: 1111637-77-4.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3-(DifluoroMethoxy)-2-Nitropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(DifluoroMethoxy)-2-Nitropyridine(1111637-77-4)
• EPA Substance Registry System: 3-(DifluoroMethoxy)-2-Nitropyridine(1111637-77-4)

Safety Data

• Hazardous Substances Data: 1111637-77-4(Hazardous Substances Data)

Usage

General Description

3-(DifluoroMethoxy)-2-Nitropyridine is a chemical compound with the molecular formula C6H4F2N2O3. It is a nitro compound and belongs to the class of pyridine derivatives. This chemical is known for its potential applications in the field of pharmaceuticals and agrochemicals. It is commonly used as an intermediate in the synthesis of various pharmaceutical products and agrochemicals. Its unique structure and properties make it a valuable building block for the development of new drugs and pesticides. The compound is also used in research and development activities for the synthesis of novel molecules with diverse biological activities.

Upstream product

• 15128-82-2 3-hydroxy-2-nitropyridine 
• 2837-90-3 sodium 2,2-dichloro-2-fluoroacetate 
• 1895-39-2 sodium chlorodifluoroacetate 
• 75-45-6 Chlorodifluoromethane 

Downstream Products

• 947249-14-1 3-(difluoromethoxy)pyridin-2-amine 
• 1188302-00-2 3-(difluoromethoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine 
• 947249-13-0 5-bromo-3-(difluoromethoxy)pyridin-2-amine 

Relevant articles and documents

Difluoro methylation reagent, preparation method and application thereof (by machine translation)

The present invention discloses a two-trifluoromethylation of the reagent, preparation method and application thereof. The invention [...] methylation reagent preparation process is simple, high yield; and the reagent can be a more moderate, high-efficiently the sulfonic acid, alcohol, carbonyl and on the α carbon atom of the difluoromethyl. (by machine translation)

TRICYCLIC DLK INHIBITORS AND USES THEREOF

The invention relates to compounds of formula (I) and salts thereof, wherein ring A and R1-R2 have any of the values defined in the specification. The compounds and salts are useful for treating DLK mediated disorders. The invention also provides pharmaceutical compositions comprising a compound of formula (I), or a pharmaceutically acceptable salt thereof, as well as methods of using said compounds, salts, or compositions as DLK inhibitors and for treating neurodegeneration diseases and disorders.

SUBSTITUTED PYRAZOLES AND USES THEREOF

The present invention provides for compounds of formula 0 and various embodiments thereof, and compositions comprising compounds of formula 0 and various embodiments thereof. In compounds of formula 0, the groups R1A, R1B, R1C, R1D, R2, R3, R4, R5 and R6 have the meaning as described herein. The present invention also provides for methods of using compounds of formula 0 and compositions comprising compounds of formula 0 as DLK inhibitors and for treating neurodegeneration diseases and disorders.