111196-05-5

Basic information

• Product Name: (2-{2-[(S)-1-(4-Nitro-phenylcarbamoyl)-ethylcarbamoyl]-ethylcarbamoyl}-ethyl)-carbamic acid benzyl ester
• CAS NO: 111196-05-5
• Molecular Weight: 485.497
• Mol File: 111196-05-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-{2-[(S)-1-(4-Nitro-phenylcarbamoyl)-ethylcarbamoyl]-ethylcarbamoyl}-ethyl)-carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2-{2-[(S)-1-(4-Nitro-phenylcarbamoyl)-ethylcarbamoyl]-ethylcarbamoyl}-ethyl)-carbamic acid benzyl ester(111196-05-5)
• EPA Substance Registry System: (2-{2-[(S)-1-(4-Nitro-phenylcarbamoyl)-ethylcarbamoyl]-ethylcarbamoyl}-ethyl)-carbamic acid benzyl ester(111196-05-5)

Safety Data

• Hazardous Substances Data: 111196-05-5(Hazardous Substances Data)

Upstream product

• 71710-18-4 N-(N-benzyloxycarbonyl-β-alanyl)-β-alanine ethyl ester 
• 2304-94-1 3-(benzyloxycarbonylamino)propanoic acid 
• 1668-13-9 L-alanine-p-nitroanilide 
• 111196-13-5 N-(N-benzyloxycarbonyl-β-alanyl)-β-alanine hydrazide 

Downstream Products

• 111196-11-3 3-carboxypropionyl-β-alanyl-β-alanyl-alanine p-nitroanilide 

Relevant articles and documents

ROLE OF AMINO ACID RESIDUES IN CHROMOGENIC SUBSTRATES CLEAVED BY PANCREATIC ELASTASE

Anionic chromogenic substrates, 3-carboxypropionyl tripeptide p-nitroanilides modified with glycine, β-alanine, alanine, leucine, and proline in positions P1, P2, and P3 were synthesized.The substrates were digested with pancreatic elastase and the values of Km, kcat, and kcat/Km were determined.Alanine plays a decisive role in position P1, substrates with glycine or β-alanine in this position are not cleaved.The substitution in P2 is dominant for proline; next follow alanine, leucine, and glycine.The substitution in P3 is the least specific one.