111279-87-9

Basic information

• Product Name: 6-Fluoro-7-(piperazin-1-yl)-9-cyclopropylisothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione
• Synonyms: 6-Fluoro-7-(piperazin-1-yl)-9-cyclopropylisothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione;9-Cyclopropyl-6-fluoro-7-(1-piperazinyl)isothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione;A-62824
• CAS NO: 111279-87-9
• Molecular Formula: C17H17 F N4 O2 S
• Molecular Weight: 360.41
• Mol File: 111279-87-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-Fluoro-7-(piperazin-1-yl)-9-cyclopropylisothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Fluoro-7-(piperazin-1-yl)-9-cyclopropylisothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione(111279-87-9)
• EPA Substance Registry System: 6-Fluoro-7-(piperazin-1-yl)-9-cyclopropylisothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione(111279-87-9)

Safety Data

• Hazardous Substances Data: 111279-87-9(Hazardous Substances Data)

Upstream product

• 110-85-0 piperazine 
• 119001-09-1 6,7-Difluoro-9-cyclopropyl-2,3,4,9-tetrahydroisothiazolo<5,4-b>quinoline-3,4-dione 
• 98349-24-7 ethyl 2,4,5-trifluorobenzoylacetate 
• 119001-08-0 Ethyl 1-cyclopropyl-2-mercapto-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate 
• 111279-72-2 ethyl 1-cyclopropyl-2-methylthio-6,7-difluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylate 
• 118959-66-3 Ethyl 3-cyclopropylamino-3-methylthio-2-(2,4,5-trifluoro)benzoylacrylate 
• 119036-36-1 ethyl 1-cyclopropyl-6,7-difluoro-2-(methylsulfinyl)-4-oxo-1,4-dihydro-3-quinoline-carboxylate 

Relevant articles and documents

8-METHOXY-9H-ISOTHIAZOLO[5,4-B]QUINOLINE-3,4-DIONES AND RELATED COMPOUNDS AS ANTI-INFECTIVE AGENTS

The invention provides compound and salts of Formula (I) and (II), disclosed herein, which includes compounds of Formula (A) and Formula (B) such compounds possess useful antimicrobial activity. The variables R2, R3, R5, R

Syntheses of 6-fluoro-7-piperazin-l-yl-9-cyclopropyl- 2,3,4,9-tetrahydroisothiazolo[5,4-b]quinoline-3,4-dione and 6-fluoro-7-piperazin-l-yl-9-p-fluorophenyl-2,3,4,9- tetrahydroisothiazolo[5,4-b]quinoline-3,4-dione[1]

The syntheses of 6-fluoro-7-piperazin-l-yl-9-cyclopropyl (or 9-p-fluorophenyl)-2,3,4,9- tetrahydroisothiazolo[5,4-b]quinoline-3,4-diones as well as novel synthesis of isothiazolo-3(2H)-one system are described. Key steps include the regiospecific displace