1112908-23-2Relevant articles and documents
Catalytic Thiourea Promoted Electrophilic Thiocyanation of Indoles and Aromatic Amines with NCS/NH4SCN
Wang, Cancan,Wang, Zhonghao,Wang, Liang,Chen, Qun,He, Mingyang
, p. 1081 - 1085 (2016)
A simple and efficient protocol for the electrophilic thiocyanation of indoles and aromatic amines with thiourea/NCS/NH4SCN system has been developed. The major features of the present procedure are the mild conditions, good yields, short reaction times, and the use of inexpensive and readily available organocatalyst. Moreover, N-chlorosuccinimide (NCS) was found to be indispensable, and thiourea could greatly promote the reaction.
Application of copper chloride dihydrate in photocatalysis of reaction of indole compound and thiocyanate compound
-
Paragraph 0074-0077, (2020/06/16)
The invention discloses an application of copper chloride dihydrate in photocatalysis of reaction of an indole compound and a thiocyanate compound. Specifically, under the atmosphere of oxygen or air,an indole compound, an ammonium thiocyanate compound and copper chloride dihydrate are added into a reaction container provided with a stirring device, ethyl alcohol is added, a stirring reaction isconducted for 20-30 hours under room-temperature illumination, and the 3-thiocyanate indole compound is obtained. According to the method, CuCl2.2H2O is directly used as a catalyst for the first timeunder the condition of not adding any photosensitizer. Besides, the efficient preparation of the 3-thiocyanate indole compound is realized, the whole process is green, efficient and easy to operate, and the application is a good method for synthesizing the 3-thiocyanate indole compound.
Visible-light-induced aerobic thiocyanation of indoles using reusable TiO2/MoS2 nanocomposite photocatalyst
Wang, Liang,Wang, Cancan,Liu, Wenjie,Chen, Qun,He, Mingyang
supporting information, p. 1771 - 1774 (2016/04/05)
TiO2/MoS2 nanocomposite photocatalyst was prepared via simple one-step hydrothermal process. This nontoxic and inexpensive photocatalyst exhibited high activity toward the thiocyanation of indoles under visible light irradiation at room temperature. Simple work-up, good yields, as well as reusability of the catalyst are the major advantages of the present method.