111293-23-3 Usage
Description
(-)-BIS[(S)-1-(ETHOXYCARBONYL)ETHYL] FUMARATE is a fumaric acid derivative featuring a symmetric structure with two stereoisomers connected by a fumarate group. This chemical compound is known for its ethoxycarbonyl ethyl groups, which contribute to its stereochemistry and reactivity in chemical reactions. It is commonly used in organic synthesis and pharmaceutical research, and has potential applications in drug development as a chiral building block. Additionally, it is utilized in the production of various fine chemicals and pharmaceutical intermediates, making it a versatile compound for both academic and industrial settings.
Uses
Used in Pharmaceutical Research and Development:
(-)-BIS[(S)-1-(ETHOXYCARBONYL)ETHYL] FUMARATE is used as a chiral building block for the development of new pharmaceutical compounds. Its unique stereochemistry allows for the creation of enantiomerically pure drugs, which can have different biological activities and reduce potential side effects.
Used in Organic Synthesis:
In the field of organic synthesis, (-)-BIS[(S)-1-(ETHOXYCARBONYL)ETHYL] FUMARATE serves as an important intermediate for the synthesis of various organic compounds. Its reactivity and ethoxycarbonyl ethyl groups make it a valuable component in the construction of complex molecular structures.
Used in the Production of Fine Chemicals:
(-)-BIS[(S)-1-(ETHOXYCARBONYL)ETHYL] FUMARATE is utilized in the production of fine chemicals, which are high-purity chemicals used in various industries such as pharmaceuticals, agriculture, and materials science. Its versatility and reactivity contribute to the synthesis of these high-quality specialty chemicals.
Used in the Production of Pharmaceutical Intermediates:
(-)-BIS[(S)-1-(ETHOXYCARBONYL)ETHYL] FUMARATE is also used in the production of pharmaceutical intermediates, which are essential building blocks in the synthesis of final drug products. Its role in creating these intermediates is crucial for the development and manufacturing of various medications.
Check Digit Verification of cas no
The CAS Registry Mumber 111293-23-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,2,9 and 3 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 111293-23:
(8*1)+(7*1)+(6*1)+(5*2)+(4*9)+(3*3)+(2*2)+(1*3)=83
83 % 10 = 3
So 111293-23-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H20O8/c1-5-19-13(17)9(3)21-11(15)7-8-12(16)22-10(4)14(18)20-6-2/h7-10H,5-6H2,1-4H3/b8-7+/t9-,10-/m0/s1
111293-23-3Relevant articles and documents
Simple and highly efficient chiral dopant molecules possessing both rod- and arch-like units
Kishikawa, Keiki,Aoyagi, Shota,Kohri, Michinari,Taniguchi, Tatsuo,Takahashi, Masahiro,Kohmoto, Shigeo
, p. 6582 - 6588 (2014)
A simple chiral dopant molecule (R)-1 with both rod- and arch-like units was prepared, and extremely large helical twisting powers (+123 to +228 μm-1) in nematic liquid crystal phases were achieved. We have demonstrated that the introduction of an arch-like unit in addition to rod-like units is highly effective in controlling the helical molecular alignment. As an application of the dopant, induction of blue phases by addition of a small amount of it was achieved. This journal is the Partner Organisations 2014.
Enantioselective synthesis of dual 5-HT4/5-HT3 serotonergic azanoradamantane SC-52491
Becker, Daniel P.,Husa, Robert K.,Moormann, Alan E.,Villamil, Clara I.,Flynn, Daniel L.
, p. 11787 - 11802 (2007/10/03)
A racemic synthesis of azanoradamantane (±)-3 was accomplished via Yamamoto's MAD-catalyzed Diels-Alder protocol. Subsequently, a scalable asymmetric synthesis of azanoradamantane benzamide SC-52491 was carried out employing Helmchen's asymmetric Diels-Alder methodology to construct all four contiguous asymmetric centers with the correct relative stereochemistry and in 99.3% e.e.
