111399-00-9

Basic information

• Product Name: (3R,3aS,6R,6aS,7aS)-3,6-dimethyl-7a-formyl-7-(3-oxobutyl)-hexahydrobenzo[1,2-b]furan-2(3H)-one
• Synonyms: (3R,3aS,6R,6aS,7aS)-3,6-dimethyl-7a-formyl-7-(3-oxobutyl)-hexahydrobenzo[1,2-b]furan-2(3H)-one
• CAS NO: 111399-00-9
• Molecular Weight: 266.337
• Mol File: 111399-00-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,3aS,6R,6aS,7aS)-3,6-dimethyl-7a-formyl-7-(3-oxobutyl)-hexahydrobenzo[1,2-b]furan-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,3aS,6R,6aS,7aS)-3,6-dimethyl-7a-formyl-7-(3-oxobutyl)-hexahydrobenzo[1,2-b]furan-2(3H)-one(111399-00-9)
• EPA Substance Registry System: (3R,3aS,6R,6aS,7aS)-3,6-dimethyl-7a-formyl-7-(3-oxobutyl)-hexahydrobenzo[1,2-b]furan-2(3H)-one(111399-00-9)

Safety Data

• Hazardous Substances Data: 111399-00-9(Hazardous Substances Data)

Upstream product

• 50906-56-4 (1R,5S,8R,9S,12R,14R)-8,12-dimethyl-4-methylidene-2,13-dioxatetracyclo[7.5.0.0^1,5.0^12,14]tetradecan-3-one 

Downstream Products

• 63968-64-9 (+)-artemisinin 
• 141039-67-0 2-(2-(3-((2R)-methoxymethylcarbonylpropyl)-2-methoxymethyloxymethylene-(6R)-methylcyclohex-(1S)-yl)ethyl)-2-methyl-1,3-dioxolane 
• 141039-66-9 2-(2-(3-(3-hydroxy-(2R)-methylpropyl)-2-methoxymethoxymethylene-(6R)-methylcyclohex-(1S)-yl)ethyl)-2-methyl-1,3-dioxolane 
• 126189-95-5 (+)-deoxyartemisinin 
• 63968-64-9 C₁₂H₁₃O₂(CH₃)3(O)(OO) 

Relevant articles and documents

Synthesis of (+)-Artemisinin and (+)-Deoxoartemisinin from arteannuin B and arteannuic acid

(+)-Artemisinin and (+)-Deoxoartemisinin were prepared for the first time from arteannuin B. The synthetic route is short and efficient, making use of the prior art for the final photo-oxygenation/cyclization reaction. A convergent route to each of the above-named products from arteannuic acid is also described. A novel oxidative lactonization reaction was developed for this sequence.