111453-56-6

Basic information

• Product Name: ethyl 3-(N-cyclopropylamino)-2-(2,4-dichloro-5-fluoro-3-nitrobenzoyl) acrylate
• Synonyms: ethyl 3-(N-cyclopropylamino)-2-(2,4-dichloro-5-fluoro-3-nitrobenzoyl) acrylate
• CAS NO: 111453-56-6
• Molecular Weight: 391.183
• Mol File: 111453-56-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: ethyl 3-(N-cyclopropylamino)-2-(2,4-dichloro-5-fluoro-3-nitrobenzoyl) acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(N-cyclopropylamino)-2-(2,4-dichloro-5-fluoro-3-nitrobenzoyl) acrylate(111453-56-6)
• EPA Substance Registry System: ethyl 3-(N-cyclopropylamino)-2-(2,4-dichloro-5-fluoro-3-nitrobenzoyl) acrylate(111453-56-6)

Safety Data

• Hazardous Substances Data: 111453-56-6(Hazardous Substances Data)

Upstream product

• 924-99-2 ethyl 3-(dimethylamino)acrylate 
• 104600-29-5 2,4-dichloro-5-fluoro-3-nitro-benzoyl chloride 
• 106809-14-7 2,4-dichloro-5-fluoro-3-nitro-benzoic acid 
• 138998-63-7 ethyl 2-[(2,4-dichloro-5-fluoro-3-nitrophenyl)carbonyl]-3-(dimethylamino)prop-2-enoate 
• 765-30-0 Cyclopropylamine 
• 106809-17-0 ethyl 2-(2,4-dichloro-5-fluoro-3-nitrobenzoyl)-3-ethoxyacrylate 

Relevant articles and documents

Heterocycles [h]fused onto 4-oxoquinolines. Part I. synthesis of 6-oxo-6,9-dihydro[1,2,5]oxadiazolo[3,4-h-quinoline-7-carboxylic acid N-oxide

Ethyl 9-cyclopropyl-4-fluoro-6-oxo-6,9-dihydro[ 1,2,5]oxadiazolo[3,4-h]quinoline-7-carboxylate N(3)-oxide (3) is synthesized via pyrolysis of the 7-azido-8-nitroquinoline-3-carboxylate precursor (6). Acid-catalyzed hydrolysis of the product (3) afforded t

Indolo[2,3-b]-, Indeno[1,2-b]- and Indeno[2,1-b]pyrido[2,3-f] quinoxaline-3-carboxylic acids and esters, processes for their preparation and their use as antiviral, antibiotic and antitumor agents

The present invention relates to novel quinoxaline derivatives represented by regioisomeric structures of quinoxalines of general formulas I and/or II, wherein the COOR1 group independently is an acid, an ester and/or a salt, Y1 and/

Quinolone Antibacterial Agents. Synthesis and Structure-Activity Relationships of 8-Substituted Quinoline-3-carboxylic Acids and 1,8-Naphthyridine-3-carboxylic Acids

A series of 7,8-disubstituted 1-cyclopropyl-6-fluoroquinoline-3-carboxylic acids, 7-substituted 1-cyclopropyl-6-fluoro-1,8-naphthyridine-3-carboxylic acids, and 10-substituted 9-fluoropyridobenzoxazine-6-carboxylic acids has been prepared and evaluated for antibacterial activity.The side chains examined at the 7-position (benzoxazine 10-position) included piperazinyl (g), 3-aminopyrrolidinyl (a), 3-(aminomethyl)pyrrolidinyl (b), and alkylated 3-(aminomethyl)pyrrolidinyl (c-f).Variations ta C-8 of the quinolone ring system included hydrogen, nitro, amino, fluorine and chlorine.The relative enhancement of in vitro activities by the side chains on the 8-hydrogen quinolone and 1,8-naphthyridine against Gram-negative organisms was a > b > g > c-f.The activity imparted to the substituted quinolone nucleus by the 8-substituent was in the order F > Cl > naphthyridine > H > benzoxazine > NH2 > NO2.These trends were retained in vivo.