111496-28-7

Basic information

• Product Name: L-Proline, 1-(2-hydroxy-4-methyl-1-oxopentyl)-, phenylmethyl ester, (S)-
• CAS NO: 111496-28-7
• Molecular Formula: C18H25NO4
• Molecular Weight: 319.401
• Mol File: 111496-28-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Proline, 1-(2-hydroxy-4-methyl-1-oxopentyl)-, phenylmethyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Proline, 1-(2-hydroxy-4-methyl-1-oxopentyl)-, phenylmethyl ester, (S)-(111496-28-7)
• EPA Substance Registry System: L-Proline, 1-(2-hydroxy-4-methyl-1-oxopentyl)-, phenylmethyl ester, (S)-(111496-28-7)

Safety Data

• Hazardous Substances Data: 111496-28-7(Hazardous Substances Data)

Upstream product

• 13748-90-8 (S)-2-hydroxyl-3,3-dimethylbutyric acid 
• 41324-66-7 H-Pro-OBzl 

Downstream Products

• 111223-29-1 (S)-1-{(S)-2-[Hydroxy-(4-phenyl-butyl)-phosphinoyloxy]-4-methyl-pentanoyl}-pyrrolidine-2-carboxylic acid benzyl ester 

Relevant articles and documents

(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme (ACE). 1. Discovery of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]- -proline, a novel orally active inhibitor of ACE

The synthesis of a series of orally active, phosphinyloxyacyl proline inhibitors of angiotensin converting enzyme (ACE) is described. The in vitro and in vivo ACE inhibitory activities are reported for each compound. The structure-activity relationship fo