1115-82-8 Usage
Description
(S)-(+)-2-METHYLGLUTARIC ACID, also known as (S)-(+)-2-MG, is an organic compound that serves as a crucial intermediate in the synthesis of various organic compounds. It is characterized by its chiral center, which gives it optical activity, and is widely utilized in the chemical and pharmaceutical industries due to its unique properties and reactivity.
Uses
Used in Chemical Synthesis:
(S)-(+)-2-METHYLGLUTARIC ACID is used as a key intermediate in the synthesis of various organic compounds, particularly those requiring chiral centers. Its optical activity makes it a valuable building block for the development of enantiomerically pure molecules, which are essential in the pharmaceutical industry for the creation of drugs with specific biological activities.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (S)-(+)-2-METHYLGLUTARIC ACID is used as a starting material for the preparation of optically active pharmaceuticals. The compound's chirality allows for the synthesis of enantiomerically pure drugs, which can have significant implications for their efficacy and safety profiles.
Used in the Preparation of Optically Active 3-Methylcyclopentene:
(S)-(+)-2-METHYLGLUTARIC ACID is specifically used in the preparation of optically active 3-methylcyclopentene, a compound with potential applications in the synthesis of various organic molecules and materials. The optical activity of 3-methylcyclopentene can be crucial for its performance in specific applications, making (S)-(+)-2-METHYLGLUTARIC ACID an essential precursor in its synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 1115-82-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,1 and 5 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1115-82:
(6*1)+(5*1)+(4*1)+(3*5)+(2*8)+(1*2)=48
48 % 10 = 8
So 1115-82-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H10O4/c1-4(6(9)10)2-3-5(7)8/h4H,2-3H2,1H3,(H,7,8)(H,9,10)/t4-/m0/s1
1115-82-8Relevant articles and documents
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Marker,Rohrmann
, p. 516 (1940)
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Stellettazole D, a cytotoxic imidazole alkaloid from the marine sponge Jaspis duoaster
Sato, Seizo,Iwata, Fumie,Takeo, Jiro,Kawahara, Hiroyuki,Kuramoto, Makoto,Uno, Hidemitsu
, p. 186 - 187 (2011)
A new cytotoxic imidazole alkaloid, stellettazole D, containing norsesquiterpene and aminopropylimidazolium units, has been isolated from the marine sponge Jaspis duoaster. The structure of stellettazole D was assigned on the basis of NMR, mass spectrometry, and IR spectral data. Stellettazole D has moderate cytotoxicity against a limited number of tumor cells.
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Takeda,K.,Minato,H.
, p. 33 - 37 (1960)
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First Direct Synthesis of Optically Active 3-Methylcyclopentene
Sliwka, Hans-Richard,Hansen, Hans-Juergen
, p. 434 - 440 (1984)
(-)-(S)- and (+)-(R)-3-methylcyclopentene (1) has been prepared in a stereochemically unambiguous synthesis.The (S)-configuration for (-)-1 was confirmed by correlation with (-)-(S)-1-methylindane.
Asymmetric hydrodimerization of styrene by a chiral zirconium complex containing a tetradentate [OSSO]-type bis(phenolato) ligand
Galdi, Nunzia,Santoro, Orlando,Oliva, Leone,Proto, Antonio,Capacchione, Carmine
scheme or table, p. 1113 - 1117 (2012/02/03)
The chiral non racemic (Λ,R,R)-[OSSO]Zr(CH2Ph) 2 (1a) activated by methylaluminoxane (MAO) and in presence of H 2 produces the chiral hydrodimer (S)-1,3-diphenylbutane with good selectivity respect to the achiral 1,4-diphenylbutane. The absolute configuration of the chiral dimer and the effect of the hydrogen pressure on the ratio between 1,3-diphenylbutane and 1,4-diphenylbutane give useful information about the regiochemistry and stereochemistry of insertion of the styrene into the Zr-H bond.
