111504-06-4

Basic information

• Product Name: N-benzyloxy-L-aspartic acid dimethyl ester
• CAS NO: 111504-06-4
• Molecular Weight: 267.282
• Mol File: 111504-06-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-benzyloxy-L-aspartic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyloxy-L-aspartic acid dimethyl ester(111504-06-4)
• EPA Substance Registry System: N-benzyloxy-L-aspartic acid dimethyl ester(111504-06-4)

Safety Data

• Hazardous Substances Data: 111504-06-4(Hazardous Substances Data)

Upstream product

• 617-55-0 dimethyl (S)-malate 
• 622-33-3 N-benzyloxyamine 
• 99147-13-4 O-tosyl-DL-malic acid dimethyl ester 
• 760-90-7 L-bromosuccinic acid dimethyl ester 
• 99088-82-1 O-tosyl-L-malic acid dimethyl ester 
• 760-90-7 DL-2-Brombernsteinsaeure-dimethylester 
• 247942-98-9 dimethyl (R)-2-fluorosulfonyloxybutane-1,4-dioate 

Relevant articles and documents

AN EFFICIENT SYNTHESIS OF N-HYDROXY-α-AMINO ACID DERIVATIVES OF HIGH OPTICAL PURITY.

Conversion of α-hydroxy esters via triflates into compounds 3 proceeds in chemical yields ranging from 78 to 89percent and with optical purities ranging from 76 to 100percent.

Interconversion of (R) and (S)-α-hydroxy esters: precursors of (S) and (R)-O-benzyl-α-hydroxylamino acid esters of high optical purity.

(R)- and (S)-α-hydroxy esters 5 are interconverted via their triflates 6 in high chemical as well as optical yields by reaction with dimethylformamide.The same triflates are efficiently converted into N-hydroxy-α-amino acid derivatives 7 of high optical purity.