111573-59-2

Basic information

• Product Name: 3-(DIMETHOXYMETHYL)-1H-PYRAZOLE
• Synonyms: BUTTPARK 85\08-12;3-(DIMETHOXYMETHYL)-1H-PYRAZOLE;3-(DIMETHOXYMETHYL)PYRAZOLE;Pyrazole-3-carboxaldehyde diMethyl acetal, 95%
• CAS NO: 111573-59-2
• Molecular Formula: C₆H₁₀N₂O₂
• Molecular Weight: 142.16
• Mol File: 111573-59-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 92-94℃/0.23mm
• Flash Point: 81.6°C
• Appearance: /
• Density: 1.148g/cm³
• Vapor Pressure: 0.136mmHg at 25°C
• Refractive Index: 1.4880
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 13.83±0.10(Predicted)
• CAS DataBase Reference: 3-(DIMETHOXYMETHYL)-1H-PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(DIMETHOXYMETHYL)-1H-PYRAZOLE(111573-59-2)
• EPA Substance Registry System: 3-(DIMETHOXYMETHYL)-1H-PYRAZOLE(111573-59-2)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 111573-59-2(Hazardous Substances Data)

Usage

General Description

3-(Dimethoxymethyl)-1H-pyrazole is a chemical compound with the molecular formula C7H12N2O2. It is a pyrazole derivative that contains two methoxy groups and a methoxymethyl group. This chemical has various applications in organic synthesis and pharmaceutical research due to its unique structure and properties. It can be used as a building block in the synthesis of various biologically active compounds and as a reagent in the formation of different heterocyclic compounds. Additionally, it has potential as a fungicide or pesticide due to its chemical properties. Overall, 3-(dimethoxymethyl)-1H-pyrazole is a versatile compound with potential applications in various fields.

InChI:InChI=1/C6H10N2O2/c1-9-6(10-2)5-3-4-7-8-5/h3-4,6H,1-2H3,(H,7,8)

Upstream product

• 67751-23-9 4-(dimethylamino)-1,1-dimethoxy-but-3-en-2-one 
• 6342-56-9 Pyruvic aldehyde dimethyl acetal 
• 67-56-1 methanol 
• 3920-50-1 3-formylpyrazole 
• 67751-23-9 (E)-4-(dimethylamino)-1,1-dimethoxybut-3-en-2-one 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 3920-50-1 3-formylpyrazole 
• 457925-22-3 5-(dimethoxymethyl)-1-[3-(phenylselanyl)propyl]-1H-pyrazole 
• 343615-84-9 C₂₂H₃₁N₃O₆S 

Relevant articles and documents

Synthetic method of tert-butyl-7-hydroxy-7,8-dihydro-4H-pyrazolo [1,5-a][1,4] diazepin-5-(6H)-carboxylate

The invention relates to a synthetic method of tert-butyl-7-hydroxy-7,8-dihydro-4H-pyrazolo [1,5-a][1,4] diazepin-5-(6H)-carboxylate and mainly solves the technical problems of low perfect ratio of a route, difficulty in reaction control, inconvenience in experiment operation and the like in the conventional synthetic process. Tert-butyl-7-hydroxy-7,8-dihydro-4H-pyrazolo [1,5-a][1,4] diazepin-5-(6H)-carboxylate is prepared from 1,1-dimethoxypropane-2-one serving as a starting material through six steps of reactions. The equation is shown in the specification. The obtained product diazepine is a useful intermediate or product for synthesis of various drugs.

Indium(III)trifluoromethanesulfonate as a mild, efficient catalyst for the formation of acetals and ketals in the presence of acid sensitive functional groups

Aldehydes and ketones, including acetophenone and benzophenone, are readily protected under mild, neutral conditions in the presence of various alcohols or orthoformates and catalytic amounts of indium(III) trifluoromethanesulfonate (0.8 mol %) under either room temperature or mild heating conditions to give the corresponding cyclic and acyclic acetals and ketals in good to excellent yields. Acid sensitive functional groups, N-Boc, THP, and TBDMS do not undergo competitive deprotection under the reported conditions.

Synthesis and biological activities of meribendan and related heterocyclic benzimidazolo-pyridazinones

The synthesis of a new heterocyclic benzimidazolo-pyridazinones is described.The new compounds were evaluated as inotropic agents with 'calcium-sensitizing' effects. 5-Methyl-6--2,3,4,5-tetrahydro-pyridazin-3-one hydrochloride (meribendan) turned out to be the most interesting compound and was chosen for development as a positive inotrope. benzimidazole / calcium sensivity / cardiotonics / inotropes / phosphodiesterase / papillary muscle / pyridazinone